R37 AI032956/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
1997	1
1998	1
2001	3
2002	1
2003	2
2005	1
2007	1
2008	1
2009	2
2010	1
2011	4
2012	3
2013	3
2014	1
2015	4
2016	2
2017	1
2018	2
2020	5
2021	4
2022	2
2023	3
2024	4

1

Metallo-β-lactamase structure and function.

Palzkill T. Palzkill T. Ann N Y Acad Sci. 2013 Jan;1277:91-104. doi: 10.1111/j.1749-6632.2012.06796.x. Epub 2012 Nov 16. Ann N Y Acad Sci. 2013. PMID: 23163348 Free PMC article. Review.

2

The mechanism of ceftazidime and cefiderocol hydrolysis by D179Y variants of KPC carbapenemases is similar and involves the formation of a long-lived covalent intermediate.

Birgy A, Nnabuife C, Palzkill T. Birgy A, et al. Antimicrob Agents Chemother. 2024 Mar 6;68(3):e0110823. doi: 10.1128/aac.01108-23. Epub 2024 Jan 23. Antimicrob Agents Chemother. 2024. PMID: 38259088 Free PMC article.

3

Klebsiella pneumoniae carbapenemase variant 44 acquires ceftazidime-avibactam resistance by altering the conformation of active-site loops.

Sun Z, Lin H, Hu L, Neetu N, Sankaran B, Wang J, Prasad BVV, Palzkill T. Sun Z, et al. J Biol Chem. 2024 Jan;300(1):105493. doi: 10.1016/j.jbc.2023.105493. Epub 2023 Nov 23. J Biol Chem. 2024. PMID: 38000656 Free PMC article.

4

Structural and Mechanistic Basis for Extended-Spectrum Drug-Resistance Mutations in Altering the Specificity of TEM, CTX-M, and KPC β-lactamases.

Palzkill T. Palzkill T. Front Mol Biosci. 2018 Feb 23;5:16. doi: 10.3389/fmolb.2018.00016. eCollection 2018. Front Mol Biosci. 2018. PMID: 29527530 Free PMC article. Review.

5

Molecular analysis of beta-lactamase structure and function.

Majiduddin FK, Materon IC, Palzkill TG. Majiduddin FK, et al. Int J Med Microbiol. 2002 Jul;292(2):127-37. doi: 10.1078/1438-4221-00198. Int J Med Microbiol. 2002. PMID: 12195735 Review.

6

Deep Sequencing of a Systematic Peptide Library Reveals Conformationally-Constrained Protein Interface Peptides that Disrupt a Protein-Protein Interaction.

Boragine DM, Huang W, Su LH, Palzkill T. Boragine DM, et al. Chembiochem. 2022 Feb 4;23(3):e202100504. doi: 10.1002/cbic.202100504. Epub 2021 Dec 7. Chembiochem. 2022. PMID: 34821011 Free PMC article.

7

A Test for the Rapid Detection of the Cefazolin Inoculum Effect in Methicillin-Susceptible Staphylococcus aureus.

Rincon S, Carvajal LP, Gomez-Villegas SI, Echeverri AM, Rios R, Dinh A, Pedroza C, Ordoñez KM, Nannini E, Sun Z, Fowler VG, Murray BE, Miller WR, Palzkill T, Diaz L, Arias CA, Reyes J. Rincon S, et al. J Clin Microbiol. 2021 Mar 19;59(4):e01938-20. doi: 10.1128/JCM.01938-20. Print 2021 Mar 19. J Clin Microbiol. 2021. PMID: 33536292 Free PMC article.

8

Network of epistatic interactions in an enzyme active site revealed by large-scale deep mutational scanning.

Judge A, Sankaran B, Hu L, Palaniappan M, Birgy A, Prasad BVV, Palzkill T. Judge A, et al. Proc Natl Acad Sci U S A. 2024 Mar 19;121(12):e2313513121. doi: 10.1073/pnas.2313513121. Epub 2024 Mar 14. Proc Natl Acad Sci U S A. 2024. PMID: 38483989 Free PMC article.

9

Exploiting the Carboxylate-Binding Pocket of β-Lactamase Enzymes Using a Focused DNA-Encoded Chemical Library.

Park S, Fan J, Chamakuri S, Palaniappan M, Sharma K, Qin X, Wang J, Tan Z, Judge A, Hu L, Sankaran B, Li F, Prasad BVV, Matzuk MM, Palzkill T. Park S, et al. J Med Chem. 2024 Jan 11;67(1):620-642. doi: 10.1021/acs.jmedchem.3c01834. Epub 2023 Dec 20. J Med Chem. 2024. PMID: 38117688

10

Streptococcus pyogenes genes that promote pharyngitis in primates.

Zhu L, Olsen RJ, Beres SB, Saavedra MO, Kubiak SL, Cantu CC, Jenkins L, Waller AS, Sun Z, Palzkill T, Porter AR, DeLeo FR, Musser JM. Zhu L, et al. JCI Insight. 2020 Jun 4;5(11):e137686. doi: 10.1172/jci.insight.137686. JCI Insight. 2020. PMID: 32493846 Free PMC article.

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