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Parasite and host kinases as targets for antimalarials.
Ong HW, Adderley J, Tobin AB, Drewry DH, Doerig C. Ong HW, et al. Expert Opin Ther Targets. 2023 Feb;27(2):151-169. doi: 10.1080/14728222.2023.2185511. Epub 2023 Mar 20. Expert Opin Ther Targets. 2023. PMID: 36942408 Free article. Review.
Identification of Novel 2,4,5-Trisubstituted Pyrimidines as Potent Dual Inhibitors of Plasmodial PfGSK3/PfPK6 with Activity against Blood Stage Parasites In Vitro.
Galal KA, Truong A, Kwarcinski F, de Silva C, Avalani K, Havener TM, Chirgwin ME, Merten E, Ong HW, Willis C, Abdelwaly A, Helal MA, Derbyshire ER, Zutshi R, Drewry DH. Galal KA, et al. J Med Chem. 2022 Oct 13;65(19):13172-13197. doi: 10.1021/acs.jmedchem.2c00996. Epub 2022 Sep 27. J Med Chem. 2022. PMID: 36166733 Free PMC article.