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Combined noncanonical NF-κB agonism and targeted BET bromodomain inhibition reverse HIV latency ex vivo.
Falcinelli SD, Peterson JJ, Turner AW, Irlbeck D, Read J, Raines SL, James KS, Sutton C, Sanchez A, Emery A, Sampey G, Ferris R, Allard B, Ghofrani S, Kirchherr JL, Baker C, Kuruc JD, Gay CL, James LI, Wu G, Zuck P, Rioja I, Furze RC, Prinjha RK, Howell BJ, Swanstrom R, Browne EP, Strahl BD, Dunham RM, Archin NM, Margolis DM. Falcinelli SD, et al. J Clin Invest. 2022 Apr 15;132(8):e157281. doi: 10.1172/JCI157281. J Clin Invest. 2022. PMID: 35426377 Free PMC article.
Machine learning approaches identify immunologic signatures of total and intact HIV DNA during long-term antiretroviral therapy.
Semenova L, Wang Y, Falcinelli S, Archin N, Cooper-Volkheimer AD, Margolis DM, Goonetilleke N, Murdoch DM, Rudin CD, Browne EP. Semenova L, et al. bioRxiv [Preprint]. 2024 Jun 25:2023.11.16.567386. doi: 10.1101/2023.11.16.567386. bioRxiv. 2024. Update in: Elife. 2024 Sep 09;13:RP94899. doi: 10.7554/eLife.94899. PMID: 38014340 Free PMC article. Updated. Preprint.
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