Leptin-loaded Extracellular Vesicles Treat Sleep-disordered Breathing in Mice with Obesity
Am J Respir Cell Mol Biol
.
2022 Dec;67(6):720-723.
doi: 10.1165/rcmb.2022-0229LE.
Authors
Carla Freire
1
,
Jacob D Ramsey
2
,
Huy Pho
1
,
Ryo Kojima
2
,
Yuling Zhao
2
,
Lenise Kim
1
,
Frederick Anokye-Danso
1
,
Slava Berger
1
,
Rexford S Ahima
1
,
Elena V Batrakova
2
,
Alexander V Kabanov
2
3
,
Vsevolod Y Polotsky
1
Affiliations
1
The Johns Hopkins School of Medicine Baltimore, Maryland.
2
University of North Carolina at Chapel Hill Chapel Hill, North Carolina.
3
M.V. Lomonosov Moscow State University Moscow, Russia.
PMID:
36454084
PMCID:
PMC9743189
DOI:
10.1165/rcmb.2022-0229LE
No abstract available
Publication types
Letter
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
MeSH terms
Animals
Extracellular Vesicles*
Leptin
Mice
Obesity / complications
Sleep Apnea Syndromes* / therapy
Substances
Leptin
Grants and funding
U18 DA052301/DA/NIDA NIH HHS/United States
R01HL128970/GF/NIH HHS/United States
R01HL133100/GF/NIH HHS/United States
R61HL156240/GF/NIH HHS/United States
R01 HL138932/HL/NHLBI NIH HHS/United States
U18DA052301/GF/NIH HHS/United States
R01HL138932/GF/NIH HHS/United States
R01 NS112019/NS/NINDS NIH HHS/United States
R01NS112019/GF/NIH HHS/United States
R01 HL128970/HL/NHLBI NIH HHS/United States
R61 HL156240/HL/NHLBI NIH HHS/United States
R01 HL133100/HL/NHLBI NIH HHS/United States