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Resistance to TOP-1 Inhibitors: Good Old Drugs Still Can Surprise Us.

Kumar S, Sherman MY. Kumar S, et al. Int J Mol Sci. 2023 Apr 13;24(8):7233. doi: 10.3390/ijms24087233. Int J Mol Sci. 2023. PMID: 37108395 Free PMC article. Review.

Evolution of Resistance to Irinotecan in Cancer Cells Involves Generation of Topoisomerase-Guided Mutations in Non-Coding Genome That Reduce the Chances of DNA Breaks.

Kumar S, Gahramanov V, Patel S, Yaglom J, Kaczmarczyk L, Alexandrov IA, Gerlitz G, Salmon-Divon M, Sherman MY. Kumar S, et al. Int J Mol Sci. 2023 May 13;24(10):8717. doi: 10.3390/ijms24108717. Int J Mol Sci. 2023. PMID: 37240063 Free PMC article.

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