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Neuronal Ndst1 depletion accelerates prion protein clearance and slows neurodegeneration in prion infection.
Aguilar-Calvo P, Malik A, Sandoval DR, Barback C, Orrù CD, Standke HG, Thomas OR, Dwyer CA, Pizzo DP, Bapat J, Soldau K, Ogawa R, Riley MB, Nilsson KPR, Kraus A, Caughey B, Iliff JJ, Vera DR, Esko JD, Sigurdson CJ. Aguilar-Calvo P, et al. PLoS Pathog. 2023 Sep 25;19(9):e1011487. doi: 10.1371/journal.ppat.1011487. eCollection 2023 Sep. PLoS Pathog. 2023. PMID: 37747931 Free PMC article.
TDP43 pathology in chronic traumatic encephalopathy retinas.
Phansalkar R, Goodwill VS, Nirschl JJ, De Lillo C, Choi J, Spurlock E, Coughlin DG, Pizzo D, Sigurdson CJ, Hiniker A, Alvarez VE, Mckee AC, Lin JH. Phansalkar R, et al. Acta Neuropathol Commun. 2023 Sep 22;11(1):152. doi: 10.1186/s40478-023-01650-6. Acta Neuropathol Commun. 2023. PMID: 37737191 Free PMC article.
Diminished Neuronal ESCRT-0 Function Exacerbates AMPA Receptor Derangement and Accelerates Prion-Induced Neurodegeneration.
Lawrence JA, Aguilar-Calvo P, Ojeda-Juárez D, Khuu H, Soldau K, Pizzo DP, Wang J, Malik A, Shay TF, Sullivan EE, Aulston B, Song SM, Callender JA, Sanchez H, Geschwind MD, Roy S, Rissman RA, Trejo J, Tanaka N, Wu C, Chen X, Patrick GN, Sigurdson CJ. Lawrence JA, et al. J Neurosci. 2023 May 24;43(21):3970-3984. doi: 10.1523/JNEUROSCI.1878-22.2023. Epub 2023 Apr 5. J Neurosci. 2023. PMID: 37019623 Free PMC article.
Prions induce an early Arc response and a subsequent reduction in mGluR5 in the hippocampus.
Ojeda-Juárez D, Lawrence JA, Soldau K, Pizzo DP, Wheeler E, Aguilar-Calvo P, Khuu H, Chen J, Malik A, Funk G, Nam P, Sanchez H, Geschwind MD, Wu C, Yeo GW, Chen X, Patrick GN, Sigurdson CJ. Ojeda-Juárez D, et al. Neurobiol Dis. 2022 Oct 1;172:105834. doi: 10.1016/j.nbd.2022.105834. Epub 2022 Jul 26. Neurobiol Dis. 2022. PMID: 35905927 Free PMC article.
11 results