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Page 1
A Cellular Mechanism to Detect and Alleviate Reductive Stress.
Manford AG, Rodríguez-Pérez F, Shih KY, Shi Z, Berdan CA, Choe M, Titov DV, Nomura DK, Rape M. Manford AG, et al. Cell. 2020 Oct 1;183(1):46-61.e21. doi: 10.1016/j.cell.2020.08.034. Epub 2020 Sep 16. Cell. 2020. PMID: 32941802 Free article.
Mitohormesis reprogrammes macrophage metabolism to enforce tolerance.
Timblin GA, Tharp KM, Ford B, Winchester JM, Wang J, Zhu S, Khan RI, Louie SK, Iavarone AT, Ten Hoeve J, Nomura DK, Stahl A, Saijo K. Timblin GA, et al. Nat Metab. 2021 May;3(5):618-635. doi: 10.1038/s42255-021-00392-w. Epub 2021 May 20. Nat Metab. 2021. PMID: 34031590 Free PMC article.
Complete biosynthesis of QS-21 in engineered yeast.
Liu Y, Zhao X, Gan F, Chen X, Deng K, Crowe SA, Hudson GA, Belcher MS, Schmidt M, Astolfi MCT, Kosina SM, Pang B, Shao M, Yin J, Sirirungruang S, Iavarone AT, Reed J, Martin LBB, El-Demerdash A, Kikuchi S, Misra RC, Liang X, Cronce MJ, Chen X, Zhan C, Kakumanu R, Baidoo EEK, Chen Y, Petzold CJ, Northen TR, Osbourn A, Scheller H, Keasling JD. Liu Y, et al. Nature. 2024 May;629(8013):937-944. doi: 10.1038/s41586-024-07345-9. Epub 2024 May 8. Nature. 2024. PMID: 38720067 Free PMC article.
DNA capture by a CRISPR-Cas9-guided adenine base editor.
Lapinaite A, Knott GJ, Palumbo CM, Lin-Shiao E, Richter MF, Zhao KT, Beal PA, Liu DR, Doudna JA. Lapinaite A, et al. Science. 2020 Jul 31;369(6503):566-571. doi: 10.1126/science.abb1390. Science. 2020. PMID: 32732424 Free PMC article.
Oxidative cyclization reagents reveal tryptophan cation-π interactions.
Xie X, Moon PJ, Crossley SWM, Bischoff AJ, He D, Li G, Dao N, Gonzalez-Valero A, Reeves AG, McKenna JM, Elledge SK, Wells JA, Toste FD, Chang CJ. Xie X, et al. Nature. 2024 Mar;627(8004):680-687. doi: 10.1038/s41586-024-07140-6. Epub 2024 Mar 6. Nature. 2024. PMID: 38448587
Redox-based reagents for chemoselective methionine bioconjugation.
Lin S, Yang X, Jia S, Weeks AM, Hornsby M, Lee PS, Nichiporuk RV, Iavarone AT, Wells JA, Toste FD, Chang CJ. Lin S, et al. Science. 2017 Feb 10;355(6325):597-602. doi: 10.1126/science.aal3316. Science. 2017. PMID: 28183972 Free PMC article.
Accelerated RNA detection using tandem CRISPR nucleases.
Liu TY, Knott GJ, Smock DCJ, Desmarais JJ, Son S, Bhuiya A, Jakhanwal S, Prywes N, Agrawal S, Díaz de León Derby M, Switz NA, Armstrong M, Harris AR, Charles EJ, Thornton BW, Fozouni P, Shu J, Stephens SI, Kumar GR, Zhao C, Mok A, Iavarone AT, Escajeda AM, McIntosh R, Kim S, Dugan EJ; IGI Testing Consortium; Pollard KS, Tan MX, Ott M, Fletcher DA, Lareau LF, Hsu PD, Savage DF, Doudna JA. Liu TY, et al. Nat Chem Biol. 2021 Sep;17(9):982-988. doi: 10.1038/s41589-021-00842-2. Epub 2021 Aug 5. Nat Chem Biol. 2021. PMID: 34354262 Free PMC article.
Machine learning predicts new anti-CRISPR proteins.
Eitzinger S, Asif A, Watters KE, Iavarone AT, Knott GJ, Doudna JA, Minhas FUAA. Eitzinger S, et al. Nucleic Acids Res. 2020 May 21;48(9):4698-4708. doi: 10.1093/nar/gkaa219. Nucleic Acids Res. 2020. PMID: 32286628 Free PMC article.
66 results