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Page 1
Cancer pharmacogenomics: strategies and challenges.
Wheeler HE, Maitland ML, Dolan ME, Cox NJ, Ratain MJ. Wheeler HE, et al. Nat Rev Genet. 2013 Jan;14(1):23-34. doi: 10.1038/nrg3352. Epub 2012 Nov 27. Nat Rev Genet. 2013. PMID: 23183705 Free PMC article. Review.
The rb pathway and cancer therapeutics.
Du W, Searle JS. Du W, et al. Curr Drug Targets. 2009 Jul;10(7):581-9. doi: 10.2174/138945009788680392. Curr Drug Targets. 2009. PMID: 19601762 Free PMC article. Review.
Inverted duplications on acentric markers: mechanism of formation.
Murmann AE, Conrad DF, Mashek H, Curtis CA, Nicolae RI, Ober C, Schwartz S. Murmann AE, et al. Hum Mol Genet. 2009 Jun 15;18(12):2241-56. doi: 10.1093/hmg/ddp160. Epub 2009 Mar 31. Hum Mol Genet. 2009. PMID: 19336476 Free PMC article.
Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy.
Wheeler HE, Gamazon ER, Wing C, Njiaju UO, Njoku C, Baldwin RM, Owzar K, Jiang C, Watson D, Shterev I, Kubo M, Zembutsu H, Winer EP, Hudis CA, Shulman LN, Nakamura Y, Ratain MJ, Kroetz DL; Cancer and Leukemia Group B; Cox NJ, Dolan ME. Wheeler HE, et al. Clin Cancer Res. 2013 Jan 15;19(2):491-9. doi: 10.1158/1078-0432.CCR-12-2618. Epub 2012 Nov 30. Clin Cancer Res. 2013. PMID: 23204130 Free PMC article.
Comprehensive genetic analysis of cytarabine sensitivity in a cell-based model identifies polymorphisms associated with outcome in AML patients.
Gamazon ER, Lamba JK, Pounds S, Stark AL, Wheeler HE, Cao X, Im HK, Mitra AK, Rubnitz JE, Ribeiro RC, Raimondi S, Campana D, Crews KR, Wong SS, Welsh M, Hulur I, Gorsic L, Hartford CM, Zhang W, Cox NJ, Dolan ME. Gamazon ER, et al. Blood. 2013 May 23;121(21):4366-76. doi: 10.1182/blood-2012-10-464149. Epub 2013 Mar 28. Blood. 2013. PMID: 23538338 Free PMC article. Clinical Trial.