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Germline PKHD1 mutations are protective against colorectal cancer.
Ward CJ, Wu Y, Johnson RA, Woollard JR, Bergstralh EJ, Cicek MS, Bakeberg J, Rossetti S, Heyer CM, Petersen GM, Lindor NM, Thibodeau SN, Harris PC, Torres VE, Hogan MC, Boardman LA. Ward CJ, et al. Hum Genet. 2011 Mar;129(3):345-9. doi: 10.1007/s00439-011-0950-8. Epub 2011 Jan 28. Hum Genet. 2011. PMID: 21274727 Free PMC article.
Smoking and colorectal cancer in Lynch syndrome: results from the Colon Cancer Family Registry and the University of Texas M.D. Anderson Cancer Center.
Pande M, Lynch PM, Hopper JL, Jenkins MA, Gallinger S, Haile RW, LeMarchand L, Lindor NM, Campbell PT, Newcomb PA, Potter JD, Baron JA, Frazier ML, Amos CI. Pande M, et al. Clin Cancer Res. 2010 Feb 15;16(4):1331-9. doi: 10.1158/1078-0432.CCR-09-1877. Epub 2010 Feb 9. Clin Cancer Res. 2010. PMID: 20145170 Free PMC article.