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Page 1
Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities.
Gay CM, Stewart CA, Park EM, Diao L, Groves SM, Heeke S, Nabet BY, Fujimoto J, Solis LM, Lu W, Xi Y, Cardnell RJ, Wang Q, Fabbri G, Cargill KR, Vokes NI, Ramkumar K, Zhang B, Della Corte CM, Robson P, Swisher SG, Roth JA, Glisson BS, Shames DS, Wistuba II, Wang J, Quaranta V, Minna J, Heymach JV, Byers LA. Gay CM, et al. Cancer Cell. 2021 Mar 8;39(3):346-360.e7. doi: 10.1016/j.ccell.2020.12.014. Epub 2021 Jan 21. Cancer Cell. 2021. PMID: 33482121 Free PMC article.
ASCL1 represses a SOX9+ neural crest stem-like state in small cell lung cancer.
Olsen RR, Ireland AS, Kastner DW, Groves SM, Spainhower KB, Pozo K, Kelenis DP, Whitney CP, Guthrie MR, Wait SJ, Soltero D, Witt BL, Quaranta V, Johnson JE, Oliver TG. Olsen RR, et al. Genes Dev. 2021 Jun;35(11-12):847-869. doi: 10.1101/gad.348295.121. Epub 2021 May 20. Genes Dev. 2021. PMID: 34016693 Free PMC article.
Charting the Fragmented Landscape of Drug Synergy.
Meyer CT, Wooten DJ, Lopez CF, Quaranta V. Meyer CT, et al. Trends Pharmacol Sci. 2020 Apr;41(4):266-280. doi: 10.1016/j.tips.2020.01.011. Epub 2020 Feb 26. Trends Pharmacol Sci. 2020. PMID: 32113653 Free PMC article. Review.
Programmatic modeling for biological systems.
Lubbock ALR, Lopez CF. Lubbock ALR, et al. Curr Opin Syst Biol. 2021 Sep;27:100343. doi: 10.1016/j.coisb.2021.05.004. Epub 2021 May 24. Curr Opin Syst Biol. 2021. PMID: 34485764 Free PMC article.
Metabolic plasticity meets gene regulation.
Paudel BB, Quaranta V. Paudel BB, et al. Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3370-3372. doi: 10.1073/pnas.1900169116. Epub 2019 Feb 8. Proc Natl Acad Sci U S A. 2019. PMID: 30737291 Free PMC article. No abstract available.
35 results