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Dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment.
Bender MJ, McPherson AC, Phelps CM, Pandey SP, Laughlin CR, Shapira JH, Medina Sanchez L, Rana M, Richie TG, Mims TS, Gocher-Demske AM, Cervantes-Barragan L, Mullett SJ, Gelhaus SL, Bruno TC, Cannon N, McCulloch JA, Vignali DAA, Hinterleitner R, Joglekar AV, Pierre JF, Lee STM, Davar D, Zarour HM, Meisel M. Bender MJ, et al. Cell. 2023 Apr 27;186(9):1846-1862.e26. doi: 10.1016/j.cell.2023.03.011. Epub 2023 Apr 6. Cell. 2023. PMID: 37028428 Free PMC article.
Obesity induces PD-1 on macrophages to suppress anti-tumour immunity.
Bader JE, Wolf MM, Lupica-Tondo GL, Madden MZ, Reinfeld BI, Arner EN, Hathaway ES, Steiner KK, Needle GA, Hatem Z, Landis MD, Faneuff EE, Blackman A, Wolf EM, Cottam MA, Ye X, Bates ME, Smart K, Wang W, Pinheiro LV, Christofides A, Smith D, Boussiotis VA, Haake SM, Beckermann KE, Wellen KE, Reinhart-King CA, Serezani CH, Lee CH, Aubrey C, Chen H, Rathmell WK, Hasty AH, Rathmell JC. Bader JE, et al. Nature. 2024 Jun;630(8018):968-975. doi: 10.1038/s41586-024-07529-3. Epub 2024 Jun 12. Nature. 2024. PMID: 38867043
Fecal microbial transplants as investigative tools in cancer.
Bohm MS, Ramesh AV, Pierre JF, Cook KL, Murphy EA, Makowski L. Bohm MS, et al. Am J Physiol Gastrointest Liver Physiol. 2024 Nov 1;327(5):G711-G726. doi: 10.1152/ajpgi.00171.2024. Epub 2024 Sep 20. Am J Physiol Gastrointest Liver Physiol. 2024. PMID: 39301964 Review.
Altered hepatic and intestinal homeostasis in a neonatal murine model of short-term total parenteral nutrition and antibiotics.
Mims TS, Kumari R, Leathem C, Antunes K, Joseph S, Yen MI, Ferstl D, Jamieson SM, Sabbar A, Biebel C, Lazarevic N, Willis NB, Henry L, Yen CE, Smith JP, Gosain A, Meisel M, Willis KA, Talati AJ, Elabiad MT, Hibl B, Pierre JF. Mims TS, et al. Am J Physiol Gastrointest Liver Physiol. 2023 Dec 1;325(6):G556-G569. doi: 10.1152/ajpgi.00129.2023. Epub 2023 Sep 27. Am J Physiol Gastrointest Liver Physiol. 2023. PMID: 37753583 Free article.
A molecular switch from tumor suppressor to oncogene in ER+ve breast cancer: Role of androgen receptor, JAK-STAT, and lineage plasticity.
Asemota S, Effah W, Holt J, Johnson D, Cripe L, Ponnusamy S, Thiyagarajan T, Khosrosereshki Y, Hwang DJ, He Y, Grimes B, Fleming MD, Pritchard FE, Hendrix A, Fan M, Jain A, Choi HY, Makowski L, Hayes DN, Miller DD, Pfeffer LM, Santhanam B, Narayanan R. Asemota S, et al. Proc Natl Acad Sci U S A. 2024 Oct;121(40):e2406837121. doi: 10.1073/pnas.2406837121. Epub 2024 Sep 23. Proc Natl Acad Sci U S A. 2024. PMID: 39312663