U19-AI31718/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
1996	1
1998	4
1999	3
2000	5
2001	3
2002	2
2003	3
2004	6
2005	2
2024	0

1

Synthesis and enantioselectivity of the antiviral effects of (R,Z)-,(S,Z)-methylenecyclopropane analogues of purine nucleosides and phosphoralaninate prodrugs: influence of heterocyclic base, type of virus and host cells.

Qiu YL, Geiser F, Kira T, Gullen E, Cheng YC, Ptak RG, Breitenbach JM, Drach JC, Hartline CB, Kern ER, Zemlicka J. Qiu YL, et al. Antivir Chem Chemother. 2000 May;11(3):191-202. doi: 10.1177/095632020001100302. Antivir Chem Chemother. 2000. PMID: 10901290 Free article.

2

Phosphorylation of beta-D-ribosylbenzimidazoles is not required for activity against human cytomegalovirus.

Krosky PM, Borysko KZ, Nassiri MR, Devivar RV, Ptak RG, Davis MG, Biron KK, Townsend LB, Drach JC. Krosky PM, et al. Antimicrob Agents Chemother. 2002 Feb;46(2):478-86. doi: 10.1128/AAC.46.2.478-486.2002. Antimicrob Agents Chemother. 2002. PMID: 11796361 Free PMC article.

3

Carbocyclic 5'-noruridine.

Hegde VR, Seley KL, Schneller SW. Hegde VR, et al. Nucleosides Nucleotides Nucleic Acids. 2000 Jan-Feb;19(1-2):269-73. doi: 10.1080/15257770008033008. Nucleosides Nucleotides Nucleic Acids. 2000. PMID: 10772714

4

Synthesis, antiviral activity, and mode of action of some 3-substituted 2,5,6-trichloroindole 2'- and 5'-deoxyribonucleosides.

Williams JD, Ptak RG, Drach JC, Townsend LB. Williams JD, et al. J Med Chem. 2004 Nov 4;47(23):5773-82. doi: 10.1021/jm0400606. J Med Chem. 2004. PMID: 15509176

5

(Z)- and (E)-2-((hydroxymethyl)cyclopropylidene)methyladenine and -guanine. New nucleoside analogues with a broad-spectrum antiviral activity.

Qiu YL, Ksebati MB, Ptak RG, Fan BY, Breitenbach JM, Lin JS, Cheng YC, Kern ER, Drach JC, Zemlicka J. Qiu YL, et al. J Med Chem. 1998 Jan 1;41(1):10-23. doi: 10.1021/jm9705723. J Med Chem. 1998. PMID: 9438017

6

Inhibition of human cytomegalovirus replication by benzimidazole nucleosides involves three distinct mechanisms.

Evers DL, Komazin G, Ptak RG, Shin D, Emmer BT, Townsend LB, Drach JC. Evers DL, et al. Antimicrob Agents Chemother. 2004 Oct;48(10):3918-27. doi: 10.1128/AAC.48.10.3918-3927.2004. Antimicrob Agents Chemother. 2004. PMID: 15388453 Free PMC article.

7

(R)-(-)- and (S)-(+)-Synadenol: synthesis, absolute configuration, and enantioselectivity of antiviral effect.

Qiu YL, Hempel A, Camerman N, Camerman A, Geiser F, Ptak RG, Breitenbach JM, Kira T, Li L, Gullen E, Cheng YC, Drach JC, Zemlicka J. Qiu YL, et al. J Med Chem. 1998 Dec 17;41(26):5257-64. doi: 10.1021/jm980323u. J Med Chem. 1998. PMID: 9857093

8

Spiropentane mimics of nucleosides: analogues of 2'-deoxyadenosine and 2'-deoxyguanosine. Synthesis of all stereoisomers, isomeric assignment, and biological activity.

Guan HP, Ksebati MB, Cheng YC, Drach JC, Kern ER, Zemlicka J. Guan HP, et al. J Org Chem. 2000 Mar 10;65(5):1280-90. doi: 10.1021/jo991030r. J Org Chem. 2000. PMID: 10814087

9

Synthesis and antiviral evaluation of polyhalogenated imidazole nucleosides: dimensional analogues of 2,5,6-trichloro-1-(beta-D-ribofuranosyl)benzimidazole.

Chien TC, Saluja SS, Drach JC, Townsend LB. Chien TC, et al. J Med Chem. 2004 Nov 4;47(23):5743-52. doi: 10.1021/jm040016q. J Med Chem. 2004. PMID: 15509173

10

Nonnucleoside pyrrolopyrimidines with a unique mechanism of action against human cytomegalovirus.

Jacobson JG, Renau TE, Nassiri MR, Sweier DG, Breitenbach JM, Townsend LB, Drach JC. Jacobson JG, et al. Antimicrob Agents Chemother. 1999 Aug;43(8):1888-94. doi: 10.1128/AAC.43.8.1888. Antimicrob Agents Chemother. 1999. PMID: 10428908 Free PMC article.

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