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In adult onset myositis, the presence of interstitial lung disease and myositis specific/associated antibodies are governed by HLA class II haplotype, rather than by myositis subtype.
Chinoy H, Salway F, Fertig N, Shephard N, Tait BD, Thomson W, Isenberg DA, Oddis CV, Silman AJ, Ollier WE, Cooper RG; UK Adult Onset Myositis Immunogenetic Collaboration (AOMIC). Chinoy H, et al. Arthritis Res Ther. 2006;8(1):R13. doi: 10.1186/ar1862. Arthritis Res Ther. 2006. PMID: 16507114 Free PMC article.
Tumour necrosis factor-alpha single nucleotide polymorphisms are not independent of HLA class I in UK Caucasians with adult onset idiopathic inflammatory myopathies.
Chinoy H, Salway F, John S, Fertig N, Tait BD, Oddis CV, Ollier WE, Cooper RG; UK Adult Onset Myositis Immunogenetic Collaboration (AOMIC). Chinoy H, et al. Rheumatology (Oxford). 2007 Sep;46(9):1411-6. doi: 10.1093/rheumatology/kem145. Epub 2007 Jun 22. Rheumatology (Oxford). 2007. PMID: 17586554