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Hyper-IgE Syndrome due to an Elusive Novel Intronic Homozygous Variant in DOCK8.
Tangye SG, Gray PE, Pillay BA, Yap JY, Figgett WA, Reeves J, Kummerfeld SK, Stoddard J, Uzel G, Jing H, Su HC, Campbell DE, Sullivan A, Burnett L, Peake J, Ma CS. Tangye SG, et al. J Clin Immunol. 2022 Jan;42(1):119-129. doi: 10.1007/s10875-021-01152-x. Epub 2021 Oct 17. J Clin Immunol. 2022. PMID: 34657245 Free PMC article.
Hematopoietic cell transplantation for DOCK8 deficiency: Results from a prospective clinical trial.
Freeman AF, Gonzalez CE, Yates B, Cole K, Little L, Flannelly E, Steinberg SM, Mo G, Piette N, Hughes TE, Cuellar-Rodriguez J, Gea-Banacloche J, Heller T, Hammoud DA, Holland SM, Kong HH, Young FD, Jing H, Kayaoglu B, Su HC, Pai SY, Hickstein DD, Shah NN. Freeman AF, et al. J Allergy Clin Immunol. 2025 Jan;155(1):176-187. doi: 10.1016/j.jaci.2024.08.021. Epub 2024 Sep 2. J Allergy Clin Immunol. 2025. PMID: 39233015 Clinical Trial.
Dedicator of cytokinesis 8-deficient CD4+ T cells are biased to a TH2 effector fate at the expense of TH1 and TH17 cells.
Tangye SG, Pillay B, Randall KL, Avery DT, Phan TG, Gray P, Ziegler JB, Smart JM, Peake J, Arkwright PD, Hambleton S, Orange J, Goodnow CC, Uzel G, Casanova JL, Lugo Reyes SO, Freeman AF, Su HC, Ma CS. Tangye SG, et al. J Allergy Clin Immunol. 2017 Mar;139(3):933-949. doi: 10.1016/j.jaci.2016.07.016. Epub 2016 Aug 20. J Allergy Clin Immunol. 2017. PMID: 27554822 Free PMC article.