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Page 1
Acetaminophen (paracetamol) oral absorption and clinical influences.
Raffa RB, Pergolizzi JV Jr, Taylor R Jr, Decker JF, Patrick JT. Raffa RB, et al. Pain Pract. 2014 Sep;14(7):668-77. doi: 10.1111/papr.12130. Epub 2013 Oct 28. Pain Pract. 2014. PMID: 26013309 Review.
Acetaminophen (paracetamol) is a widely used nonopioid, non-NSAID analgesic that is effective against a variety of pain types, but the consequences of overdose can be severe. Because acetaminophen is so widely available as a single agent and is increas …
Acetaminophen (paracetamol) is a widely used nonopioid, non-NSAID analgesic that is effective against a variety of pain types, …
Updated guidelines for the management of paracetamol poisoning in Australia and New Zealand.
Chiew AL, Reith D, Pomerleau A, Wong A, Isoardi KZ, Soderstrom J, Buckley NA. Chiew AL, et al. Med J Aust. 2020 Mar;212(4):175-183. doi: 10.5694/mja2.50428. Epub 2019 Dec 1. Med J Aust. 2020. PMID: 31786822 Review.
INTRODUCTION: Paracetamol is a common agent taken in deliberate self-poisoning and in accidental overdose in adults and children. ...Cases that require different management include modified release paracetamol overdoses, large or massive overdoses, …
INTRODUCTION: Paracetamol is a common agent taken in deliberate self-poisoning and in accidental overdose in adults and …
Acetaminophen hepatoxicity.
Broughan TA, Soloway RD. Broughan TA, et al. Dig Dis Sci. 2000 Aug;45(8):1553-8. doi: 10.1023/a:1005508910222. Dig Dis Sci. 2000. PMID: 11007105
To determine the influence of psychosocial factors in accidental and deliberate acetaminophen overdose, we reviewed the charts of 207 overdose patients, and 48 met our criteria for acetaminophen toxicity. ...Alcohol abuse was associated with a l …
To determine the influence of psychosocial factors in accidental and deliberate acetaminophen overdose, we reviewed the …
Toxicology in the emergency department: what's new?
Motohashi K, Thanacoody RH. Motohashi K, et al. Br J Hosp Med (Lond). 2022 Sep 2;83(9):1-16. doi: 10.12968/hmed.2022.0313. Epub 2022 Sep 13. Br J Hosp Med (Lond). 2022. PMID: 36193928 Free article. Review.
Intentional and accidental drug overdose, recreational drug use and exposure to toxic substances are common reasons for people presenting to emergency departments. ...This review discusses new developments in the management of paracetamol overdose. Sev …
Intentional and accidental drug overdose, recreational drug use and exposure to toxic substances are common reasons for people …
When acetaminophen use becomes toxic. Treating acute accidental and intentional overdose.
Salgia AD, Kosnik SD. Salgia AD, et al. Postgrad Med. 1999 Apr;105(4):81-4, 87, 90. doi: 10.3810/pgm.1999.04.673. Postgrad Med. 1999. PMID: 10223088 Review.
Whether accidental or intentional, acetaminophen poisoning is not uncommon; in fact, it is the most common drug-induced cause of liver failure. ...In diagnosing acetaminophen toxicity, adequate history taking and serial measurements of acetaminophen le …
Whether accidental or intentional, acetaminophen poisoning is not uncommon; in fact, it is the most common drug-induced cause …
Paracetamol induced hepatotoxicity.
Mahadevan SB, McKiernan PJ, Davies P, Kelly DA. Mahadevan SB, et al. Arch Dis Child. 2006 Jul;91(7):598-603. doi: 10.1136/adc.2005.076836. Epub 2006 Mar 17. Arch Dis Child. 2006. PMID: 16547087 Free PMC article.
AIM: To identify the clinical and biochemical risk factors associated with outcome of paracetamol induced significant hepatotoxicity in children. METHODS: Retrospective case notes review of those with paracetamol overdose admitted from 1992 to 2002. ...Althou …
AIM: To identify the clinical and biochemical risk factors associated with outcome of paracetamol induced significant hepatotoxicity …
Impact of acetaminophen product labelling changes in Canada on hospital admissions for accidental acetaminophen overdose: a population-based study.
Antoniou T, Guan Q, Martins D, Gomes T. Antoniou T, et al. CMAJ. 2022 Apr 19;194(15):E542-E548. doi: 10.1503/cmaj.210842. CMAJ. 2022. PMID: 35440502 Free PMC article.
We sought to explore whether these changes affected rates of hospital admission for accidental acetaminophen overdose. METHODS: We conducted a population-based study of hospital admissions for accidental acetaminophen overdose in 9 Canadi …
We sought to explore whether these changes affected rates of hospital admission for accidental acetaminophen overdose. …
Management of chronic noncancer pain in depressed patients.
Barkin RL, Barkin SJ, Irving GA, Gordon A. Barkin RL, et al. Postgrad Med. 2011 Sep;123(5):143-54. doi: 10.3810/pgm.2011.09.2470. Postgrad Med. 2011. PMID: 21904097 Review.
Chronic pain and depression each increase the risk of licit and illicit substance abuse, including the abuse of opioids, and of suicide. Patients attempting suicide may overdose on opioids, which are commonly perceived as potentially harmful, or acetaminophen, an ag …
Chronic pain and depression each increase the risk of licit and illicit substance abuse, including the abuse of opioids, and of suicide. Pat …
Paracetamol poisoning: a population-based study from Iceland.
Friðriksdóttir ÞA, Jónsdóttir F, Snook CP, Líndal H, Björnsson ES. Friðriksdóttir ÞA, et al. Scand J Gastroenterol. 2021 Jul;56(7):832-839. doi: 10.1080/00365521.2021.1921254. Epub 2021 May 11. Scand J Gastroenterol. 2021. PMID: 33974465
Overall, six (1.1%) cases were fatal in which paracetamol contributed to the cause of death, with accidental poisoning found in 67% (4/6). ...Most patients had favourable outcomes. Intentional overdose was most common in young females, whereas accidental …
Overall, six (1.1%) cases were fatal in which paracetamol contributed to the cause of death, with accidental poisoning found i …
73 results