Extracellular nicotinamide adenine dinucleotide induces t cell apoptosis in vivo and in vitro.
Liu ZX, Azhipa O, Okamoto S, Govindarajan S, Dennert G.
Liu ZX, et al.
J Immunol. 2001 Nov 1;167(9):4942-7. doi: 10.4049/jimmunol.167.9.4942.
J Immunol. 2001.
PMID: 11673500
In this study, we analyze the reasons for these effects and report that contact of T cells with NAD causes cell death. Naive T cells when incubated with NAD and adoptively transferred into semiallogeneic mice fail to cause graft-vs-host disease, and when injected into syng …
In this study, we analyze the reasons for these effects and report that contact of T cells with NAD causes cell death. Naive T cells …