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38 results

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Page 1
Single-Agent Divarasib (GDC-6036) in Solid Tumors with a KRAS G12C Mutation.
Sacher A, LoRusso P, Patel MR, Miller WH Jr, Garralda E, Forster MD, Santoro A, Falcon A, Kim TW, Paz-Ares L, Bowyer S, de Miguel M, Han SW, Krebs MG, Lee JS, Cheng ML, Arbour K, Massarelli E, Choi Y, Shi Z, Mandlekar S, Lin MT, Royer-Joo S, Chang J, Dharia NV, Schutzman JL, Desai J; GO42144 Investigator and Study Group. Sacher A, et al. N Engl J Med. 2023 Aug 24;389(8):710-721. doi: 10.1056/NEJMoa2303810. N Engl J Med. 2023. PMID: 37611121 Free article. Clinical Trial.
Circulating Tumor DNA Dynamics Reveal KRAS G12C Mutation Heterogeneity and Response to Treatment with the KRAS G12C Inhibitor Divarasib in Solid Tumors.
Choi Y, Dharia NV, Jun T, Chang J, Royer-Joo S, Yau KK, Assaf ZJ, Aimi J, Sivakumar S, Montesion M, Sacher A, LoRusso P, Desai J, Schutzman JL, Shi Z; and the GO42144 study group. Choi Y, et al. Among authors: aimi j. Clin Cancer Res. 2024 Sep 3;30(17):3788-3797. doi: 10.1158/1078-0432.CCR-24-0255. Clin Cancer Res. 2024. PMID: 38995268 Free PMC article. Clinical Trial.
Giredestrant reverses progesterone hypersensitivity driven by estrogen receptor mutations in breast cancer.
Liang J, Ingalla ER, Yao X, Wang BE, Tai L, Giltnane J, Liang Y, Daemen A, Moore HM, Aimi J, Chang CW, Gates MR, Eng-Wong J, Tam L, Bacarro N, Roose-Girma M, Bellet M, Hafner M, Metcalfe C. Liang J, et al. Among authors: aimi j. Sci Transl Med. 2022 Sep 21;14(663):eabo5959. doi: 10.1126/scitranslmed.abo5959. Epub 2022 Sep 21. Sci Transl Med. 2022. PMID: 36130016
Solvent-free luminescent organic liquids.
Santhosh Babu S, Aimi J, Ozawa H, Shirahata N, Saeki A, Seki S, Ajayaghosh A, Möhwald H, Nakanishi T. Santhosh Babu S, et al. Among authors: aimi j. Angew Chem Int Ed Engl. 2012 Apr 2;51(14):3391-5. doi: 10.1002/anie.201108853. Epub 2012 Feb 28. Angew Chem Int Ed Engl. 2012. PMID: 22374578
Telomerase inhibitors--oligonucleotide phosphoramidates as potential therapeutic agents.
Gryaznov S, Pongracz K, Matray T, Schultz R, Pruzan R, Aimi J, Chin A, Harley C, Shea-Herbert B, Shay J, Oshima Y, Asai A, Yamashita Y. Gryaznov S, et al. Among authors: aimi j. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):401-10. doi: 10.1081/NCN-100002314. Nucleosides Nucleotides Nucleic Acids. 2001. PMID: 11563055
38 results