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Page 1
Anti-Integrin αvβ6 Autoantibodies Are a Novel Biomarker That Antedate Ulcerative Colitis.
Livanos AE, Dunn A, Fischer J, Ungaro RC, Turpin W, Lee SH, Rui S, Del Valle DM, Jougon JJ, Martinez-Delgado G, Riddle MS, Murray JA, Laird RM, Torres J, Agrawal M, Magee JS, Dervieux T, Gnjatic S, Sheppard D, Sands BE, Porter CK, Croitoru K, Petralia F; CCC-GEM Project Research Consortium; OSCCAR Consortium; Colombel JF, Mehandru S. Livanos AE, et al. Gastroenterology. 2023 Apr;164(4):619-629. doi: 10.1053/j.gastro.2022.12.042. Epub 2023 Jan 10. Gastroenterology. 2023. PMID: 36634824 Free PMC article.
Altered Gut Microbiome Composition and Function Are Associated With Gut Barrier Dysfunction in Healthy Relatives of Patients With Crohn's Disease.
Leibovitzh H, Lee SH, Xue M, Raygoza Garay JA, Hernandez-Rocha C, Madsen KL, Meddings JB, Guttman DS, Espin-Garcia O, Smith MI, Goethel A, Griffiths AM, Moayyedi P, Steinhart AH, Panaccione R, Huynh HQ, Jacobson K, Aumais G, Mack DR, Abreu MT, Bernstein CN, Marshall JK, Turner D, Xu W; CCC GEM Project Research Consortium; Turpin W, Croitoru K. Leibovitzh H, et al. Gastroenterology. 2022 Nov;163(5):1364-1376.e10. doi: 10.1053/j.gastro.2022.07.004. Epub 2022 Jul 16. Gastroenterology. 2022. PMID: 35850197
Gut Microbiome Composition Is Associated With Future Onset of Crohn's Disease in Healthy First-Degree Relatives.
Raygoza Garay JA, Turpin W, Lee SH, Smith MI, Goethel A, Griffiths AM, Moayyedi P, Espin-Garcia O, Abreu M, Aumais GL, Bernstein CN, Biron IA, Cino M, Deslandres C, Dotan I, El-Matary W, Feagan B, Guttman DS, Huynh H, Dieleman LA, Hyams JS, Jacobson K, Mack D, Marshall JK, Otley A, Panaccione R, Ropeleski M, Silverberg MS, Steinhart AH, Turner D, Yerushalmi B, Paterson AD, Xu W; CCC GEM Project Research Consortium; Croitoru K. Raygoza Garay JA, et al. Gastroenterology. 2023 Sep;165(3):670-681. doi: 10.1053/j.gastro.2023.05.032. Epub 2023 May 30. Gastroenterology. 2023. PMID: 37263307
Environmental Factors Associated With Risk of Crohn's Disease Development in the Crohn's and Colitis Canada - Genetic, Environmental, Microbial Project.
Xue M, Leibovitzh H, Jingcheng S, Neustaeter A, Dong M, Xu W, Espin-Garcia O, Griffiths AM, Steinhart AH, Turner D, Huynh HQ, Dieleman LA, Panaccione R, Aumais G, Bressler B, Bitton A, Murthy S, Marshall JK, Hyams JS, Otley A, Bernstein CN, Moayyedi P, El-Matary W, Fich A, Denson LA, Ropeleski MJ, Abreu MT, Deslandres C, Cino M, Avni-Biron I, Lee SH, Turpin W; CCC GEM Project Research Consortium; Croitoru K. Xue M, et al. Clin Gastroenterol Hepatol. 2024 Sep;22(9):1889-1897.e12. doi: 10.1016/j.cgh.2024.03.049. Epub 2024 May 16. Clin Gastroenterol Hepatol. 2024. PMID: 38759825
Early Life Exposure to Parental Crohn's Disease Is Associated With Offspring's Gut Microbiome, Gut Permeability, and Increased Risk of Future Crohn's Disease.
Lee SH, Bushra M, Qiu L, Griffiths AM, Turpin W, Croitoru K; Crohn’s and Colitis Canada-Genetic, Environmental, Microbial (CCC-GEM) Project Research Consortium; Lee SH, Bushra M, Qiu L, Shao J, Olivera PA, Leibovitzh H, Xue M, Xu W, Espin-Garcia O, Amuais GL, Huynh HQ, Panaccione R, Steinhart AH, Cino M, Mack D, Marshall J, Ropeleski M, Bitton A, Jacobson K, McGrath J, Yerushalmi B, Abreu MT, Bernstein CN, Radford-Smith G, Lees C, Turner D, Madsen K, Guttman DS, Silverberg M, Griffiths AM, Moayyedi P, Turpin W, Beck P, Dieleman L, Feagan BG, Kaplan G, Krause DO, Seidman E, Snapper S, Stadnyk A, Surette M, Walters T, Vallance B, Critch J, Denson L, Deslandres C, El-Matary W, Herfarth H, Higgins P, Hyams J, Otley A, Hedin C, Hussey S, Keljo D, Kevans D, Murthy S, Parekh N, Plamondon S, Rosh J, Rubin D, Schultz M, Siegel C, Croitoru K. Lee SH, et al. Gastroenterology. 2024 Oct 9:S0016-5085(24)05539-2. doi: 10.1053/j.gastro.2024.09.033. Online ahead of print. Gastroenterology. 2024. PMID: 39384162 Free article. No abstract available.
Development and Validation of an Integrative Risk Score for Future Risk of Crohn's Disease in Healthy First-Degree Relatives: A Multicenter Prospective Cohort Study.
Lee SH, Turpin W, Espin-Garcia O, Xu W, Croitoru K; Crohn's and Colitis Canada-Genetic, Environmental, Microbial (CCC-GEM) Project Research Consortium. Lee SH, et al. Gastroenterology. 2025 Jan;168(1):150-153.e4. doi: 10.1053/j.gastro.2024.08.021. Epub 2024 Aug 30. Gastroenterology. 2025. PMID: 39209122 Free article. No abstract available.
Analysis of Genetic Association of Intestinal Permeability in Healthy First-degree Relatives of Patients with Crohn's Disease.
Turpin W, Espin-Garcia O, Bedrani L, Madsen K, Meddings JB, Raygoza Garay JA, Silverberg MS, Smith MI, Griffiths AM, Moayyedi P, Marshall JK, Mack D, Seidman EG, Ropeleski M, Feagan BG, Jacobson K, Turner D, Walters T, Paterson AD; CCC GEM Project Research Consortium; Xu W, Croitoru K. Turpin W, et al. Inflamm Bowel Dis. 2019 Oct 18;25(11):1796-1804. doi: 10.1093/ibd/izz116. Inflamm Bowel Dis. 2019. PMID: 31251335