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Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells.
Green AC, Marttila P, Kiweler N, Chalkiadaki C, Wiita E, Cookson V, Lesur A, Eiden K, Bernardin F, Vallin KSA, Borhade S, Long M, Ghahe EK, Jiménez-Alonso JJ, Jemth AS, Loseva O, Mortusewicz O, Meyers M, Viry E, Johansson AI, Hodek O, Homan E, Bonagas N, Ramos L, Sandberg L, Frödin M, Moussay E, Slipicevic A, Letellier E, Paggetti J, Sørensen CS, Helleday T, Henriksson M, Meiser J. Green AC, et al. Among authors: eiden k. Nat Metab. 2023 Apr;5(4):642-659. doi: 10.1038/s42255-023-00771-5. Epub 2023 Apr 3. Nat Metab. 2023. PMID: 37012496 Free PMC article.
Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis.
Kiweler N, Delbrouck C, Pozdeev VI, Neises L, Soriano-Baguet L, Eiden K, Xian F, Benzarti M, Haase L, Koncina E, Schmoetten M, Jaeger C, Noman MZ, Vazquez A, Janji B, Dittmar G, Brenner D, Letellier E, Meiser J. Kiweler N, et al. Among authors: eiden k. Nat Commun. 2022 May 16;13(1):2699. doi: 10.1038/s41467-022-30363-y. Nat Commun. 2022. PMID: 35577770 Free PMC article.
Opioids: nonmedical use and abuse in older children.
Frese WA, Eiden K. Frese WA, et al. Among authors: eiden k. Pediatr Rev. 2011 Apr;32(4):e44-52. doi: 10.1542/pir.32-4-e44. Pediatr Rev. 2011. PMID: 21460089 Review. No abstract available.