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Protein restriction slows the development and progression of pathology in a mouse model of Alzheimer's disease.
Babygirija R, Sonsalla MM, Mill J, James I, Han JH, Green CL, Calubag MF, Wade G, Tobon A, Michael J, Trautman MM, Matoska R, Yeh CY, Grunow I, Pak HH, Rigby MJ, Baldwin DA, Niemi NM, Denu JM, Puglielli L, Simcox J, Lamming DW. Babygirija R, et al. Among authors: grunow i. Nat Commun. 2024 Jun 18;15(1):5217. doi: 10.1038/s41467-024-49589-z. Nat Commun. 2024. PMID: 38890307 Free PMC article.
Protein restriction slows the development and progression of Alzheimer's disease in mice.
Babygirija R, Sonsalla MM, Mill J, James I, Han JH, Green CL, Calubag MF, Wade G, Tobon A, Michael J, Trautman MM, Matoska R, Yeh CY, Grunow I, Pak HH, Rigby MJ, Baldwin DA, Niemi NM, Denu JM, Puglielli L, Simcox J, Lamming DW. Babygirija R, et al. Among authors: grunow i. Res Sq [Preprint]. 2024 Apr 24:rs.3.rs-3342413. doi: 10.21203/rs.3.rs-3342413/v2. Res Sq. 2024. Update in: Nat Commun. 2024 Jun 18;15(1):5217. doi: 10.1038/s41467-024-49589-z PMID: 37790423 Free PMC article. Updated. Preprint.
Fasting is required for many of the benefits of calorie restriction in the 3xTg mouse model of Alzheimer's disease.
Babygirija R, Han JH, Sonsalla MM, Matoska R, Calubag MF, Green CL, Tobon A, Yeh CY, Vertein D, Schlorf S, Illiano J, Liu Y, Grunow I, Rigby MJ, Puglielli L, Harris DA, Denu JM, Lamming DW. Babygirija R, et al. Among authors: grunow i. bioRxiv [Preprint]. 2024 Sep 24:2024.09.19.613904. doi: 10.1101/2024.09.19.613904. bioRxiv. 2024. PMID: 39386545 Free PMC article. Preprint.
Acarbose ameliorates Western diet-induced metabolic and cognitive impairments in the 3xTg mouse model of Alzheimer's disease.
Sonsalla MM, Babygirija R, Johnson M, Cai S, Cole M, Yeh CY, Grunow I, Liu Y, Vertein D, Calubag MF, Trautman ME, Green CL, Rigby MJ, Puglielli L, Lamming DW. Sonsalla MM, et al. Among authors: grunow i. bioRxiv [Preprint]. 2024 Jul 2:2024.06.27.600472. doi: 10.1101/2024.06.27.600472. bioRxiv. 2024. Update in: Geroscience. 2024 Sep 14. doi: 10.1007/s11357-024-01337-3 PMID: 39005334 Free PMC article. Updated. Preprint.