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Contraceptive implant use duration is not associated with breakthrough pregnancy among women living with HIV and using efavirenz: a retrospective, longitudinal analysis.
Stalter RM, Amorim G, Mocello AR, Jakait B, Shepherd BE, Musick B, Bernard C, Bukusi EA, Wools-Kaloustian K, Cohen CR, Yiannoutsos CT, Patel RC; Implant/Efavirenz Study Group and the East Africa IeDEA regional consortium. Stalter RM, et al. J Int AIDS Soc. 2022 Sep;25(9):e26001. doi: 10.1002/jia2.26001. J Int AIDS Soc. 2022. PMID: 36073977 Free PMC article.
However, recent pharmacokinetic data have shown drug-drug interactions between implants and efavirenz-containing antiretroviral therapy (ART), reducing the effectiveness of the implants. ...CONCLUSIONS: We did not find evidence to suggest implants
However, recent pharmacokinetic data have shown drug-drug interactions between implants and efavirenz-containing antire …
Pregnancies among women living with HIV using contraceptives and antiretroviral therapy in western Kenya: a retrospective, cohort study.
Patel RC, Amorim G, Jakait B, Shepherd BE, Mocello AR, Musick B, Bernard C, Onono M, Bukusi EA, Wools-Kaloustian K, Cohen CR, Yiannoutsos CT; Implant/Efavirenz Study Group and the East Africa IeDEA Regional Consortium. Patel RC, et al. BMC Med. 2021 Aug 13;19(1):178. doi: 10.1186/s12916-021-02043-z. BMC Med. 2021. PMID: 34384443 Free PMC article.
Among efavirenz users, the aIRR of pregnancy for depomedroxyprogesterone acetate (DMPA) vs. implant use was 1.8 (95% CI 1.5, 2.1) in EMR only and 2.4 (95% CI 1.0, 6.1) using validated data. CONCLUSION: Pregnancy rates are higher when contraceptive implants are conco …
Among efavirenz users, the aIRR of pregnancy for depomedroxyprogesterone acetate (DMPA) vs. implant use was 1.8 (95% CI 1.5, 2.1) in …