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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1959 4
1960 1
1961 2
1963 4
1965 5
1966 3
1967 5
1968 2
1969 4
1970 6
1971 3
1972 6
1973 8
1974 6
1975 1
1976 5
1977 8
1978 8
1979 8
1980 1
1981 5
1982 8
1983 15
1984 13
1985 5
1986 5
1987 9
1988 8
1989 10
1990 6
1991 4
1992 8
1993 11
1994 8
1995 12
1996 13
1997 6
1998 7
1999 5
2000 7
2001 4
2002 10
2003 4
2004 6
2005 4
2006 12
2007 13
2008 9
2009 8
2010 19
2011 10
2012 18
2013 11
2014 16
2015 19
2016 30
2017 26
2018 23
2019 30
2020 27
2021 47
2022 32
2023 42
2024 53
2025 6

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677 results

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Page 1
Cellular senescence and senolytics: the path to the clinic.
Chaib S, Tchkonia T, Kirkland JL. Chaib S, et al. Among authors: kirkland jl. Nat Med. 2022 Aug;28(8):1556-1568. doi: 10.1038/s41591-022-01923-y. Epub 2022 Aug 11. Nat Med. 2022. PMID: 35953721 Free PMC article. Review.
Cellular senescence: the good, the bad and the unknown.
Huang W, Hickson LJ, Eirin A, Kirkland JL, Lerman LO. Huang W, et al. Among authors: kirkland jl. Nat Rev Nephrol. 2022 Oct;18(10):611-627. doi: 10.1038/s41581-022-00601-z. Epub 2022 Aug 3. Nat Rev Nephrol. 2022. PMID: 35922662 Free PMC article. Review.
A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues.
Saul D, Kosinsky RL, Atkinson EJ, Doolittle ML, Zhang X, LeBrasseur NK, Pignolo RJ, Robbins PD, Niedernhofer LJ, Ikeno Y, Jurk D, Passos JF, Hickson LJ, Xue A, Monroe DG, Tchkonia T, Kirkland JL, Farr JN, Khosla S. Saul D, et al. Among authors: kirkland jl. Nat Commun. 2022 Aug 16;13(1):4827. doi: 10.1038/s41467-022-32552-1. Nat Commun. 2022. PMID: 35974106 Free PMC article.
Cellular senescence mediates fibrotic pulmonary disease.
Schafer MJ, White TA, Iijima K, Haak AJ, Ligresti G, Atkinson EJ, Oberg AL, Birch J, Salmonowicz H, Zhu Y, Mazula DL, Brooks RW, Fuhrmann-Stroissnigg H, Pirtskhalava T, Prakash YS, Tchkonia T, Robbins PD, Aubry MC, Passos JF, Kirkland JL, Tschumperlin DJ, Kita H, LeBrasseur NK. Schafer MJ, et al. Among authors: kirkland jl. Nat Commun. 2017 Feb 23;8:14532. doi: 10.1038/ncomms14532. Nat Commun. 2017. PMID: 28230051 Free PMC article.
Senolytics improve physical function and increase lifespan in old age.
Xu M, Pirtskhalava T, Farr JN, Weigand BM, Palmer AK, Weivoda MM, Inman CL, Ogrodnik MB, Hachfeld CM, Fraser DG, Onken JL, Johnson KO, Verzosa GC, Langhi LGP, Weigl M, Giorgadze N, LeBrasseur NK, Miller JD, Jurk D, Singh RJ, Allison DB, Ejima K, Hubbard GB, Ikeno Y, Cubro H, Garovic VD, Hou X, Weroha SJ, Robbins PD, Niedernhofer LJ, Khosla S, Tchkonia T, Kirkland JL. Xu M, et al. Among authors: kirkland jl. Nat Med. 2018 Aug;24(8):1246-1256. doi: 10.1038/s41591-018-0092-9. Epub 2018 Jul 9. Nat Med. 2018. PMID: 29988130 Free PMC article.
Strategies for Targeting Senescent Cells in Human Disease.
Gasek NS, Kuchel GA, Kirkland JL, Xu M. Gasek NS, et al. Among authors: kirkland jl. Nat Aging. 2021 Oct;1(10):870-879. doi: 10.1038/s43587-021-00121-8. Epub 2021 Oct 7. Nat Aging. 2021. PMID: 34841261 Free PMC article. Review.
Guidelines for minimal information on cellular senescence experimentation in vivo.
Ogrodnik M, Carlos Acosta J, Adams PD, d'Adda di Fagagna F, Baker DJ, Bishop CL, Chandra T, Collado M, Gil J, Gorgoulis V, Gruber F, Hara E, Jansen-Dürr P, Jurk D, Khosla S, Kirkland JL, Krizhanovsky V, Minamino T, Niedernhofer LJ, Passos JF, Ring NAR, Redl H, Robbins PD, Rodier F, Scharffetter-Kochanek K, Sedivy JM, Sikora E, Witwer K, von Zglinicki T, Yun MH, Grillari J, Demaria M. Ogrodnik M, et al. Among authors: kirkland jl. Cell. 2024 Aug 8;187(16):4150-4175. doi: 10.1016/j.cell.2024.05.059. Cell. 2024. PMID: 39121846 Free article. Review.
The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.
Zhu Y, Tchkonia T, Pirtskhalava T, Gower AC, Ding H, Giorgadze N, Palmer AK, Ikeno Y, Hubbard GB, Lenburg M, O'Hara SP, LaRusso NF, Miller JD, Roos CM, Verzosa GC, LeBrasseur NK, Wren JD, Farr JN, Khosla S, Stout MB, McGowan SJ, Fuhrmann-Stroissnigg H, Gurkar AU, Zhao J, Colangelo D, Dorronsoro A, Ling YY, Barghouthy AS, Navarro DC, Sano T, Robbins PD, Niedernhofer LJ, Kirkland JL. Zhu Y, et al. Among authors: kirkland jl. Aging Cell. 2015 Aug;14(4):644-58. doi: 10.1111/acel.12344. Epub 2015 Apr 22. Aging Cell. 2015. PMID: 25754370 Free PMC article.
COVID-19 and cellular senescence.
Schmitt CA, Tchkonia T, Niedernhofer LJ, Robbins PD, Kirkland JL, Lee S. Schmitt CA, et al. Among authors: kirkland jl. Nat Rev Immunol. 2023 Apr;23(4):251-263. doi: 10.1038/s41577-022-00785-2. Epub 2022 Oct 5. Nat Rev Immunol. 2023. PMID: 36198912 Free PMC article. Review.
677 results