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Page 1
Long-Lived Plasma Cells Are Contained within the CD19(-)CD38(hi)CD138(+) Subset in Human Bone Marrow.
Halliley JL, Tipton CM, Liesveld J, Rosenberg AF, Darce J, Gregoretti IV, Popova L, Kaminiski D, Fucile CF, Albizua I, Kyu S, Chiang KY, Bradley KT, Burack R, Slifka M, Hammarlund E, Wu H, Zhao L, Walsh EE, Falsey AR, Randall TD, Cheung WC, Sanz I, Lee FE. Halliley JL, et al. Among authors: kyu s. Immunity. 2015 Jul 21;43(1):132-45. doi: 10.1016/j.immuni.2015.06.016. Epub 2015 Jul 14. Immunity. 2015. PMID: 26187412 Free PMC article.
Distinct transcriptomes and autocrine cytokines underpin maturation and survival of antibody-secreting cells in systemic lupus erythematosus.
Chen W, Hong SH, Jenks SA, Anam FA, Tipton CM, Woodruff MC, Hom JR, Cashman KS, Faliti CE, Wang X, Kyu S, Wei C, Scharer CD, Mi T, Hicks S, Hartson L, Nguyen DC, Khosroshahi A, Lee S, Wang Y, Bugrovsky R, Ishii Y, Lee FE, Sanz I. Chen W, et al. Among authors: kyu s. Nat Commun. 2024 Mar 1;15(1):1899. doi: 10.1038/s41467-024-46053-w. Nat Commun. 2024. PMID: 38429276 Free PMC article.
Patients taking benralizumab, dupilumab, or mepolizumab have lower postvaccination SARS-CoV-2 immunity.
Runnstrom MC, Lamothe PA, Faliti CE, Cheedarla N, Moreno A, Suthar MS, Nahata R, Ravindran M, Haddad NS, Morrison-Porter A, Quehl H, Ramonell RP, Woodruff M, Anam F, Zhang R, Swenson C, Polito C, Neveu W, Patel R, Smirnova N, Nguyen DC, Kim C, Hentenaar I, Kyu S, Usman S, Ngo T, Guo Z, Wu H, Daiss JL, Park J, Manning KE, Wali B, Ellis ML, Sharma S, Holguin F, Cheedarla S, Neish AS, Roback JD, Sanz I, Eun-Hyung Lee F. Runnstrom MC, et al. Among authors: kyu s. J Allergy Clin Immunol. 2024 Aug;154(2):435-446. doi: 10.1016/j.jaci.2024.03.029. Epub 2024 Jun 13. J Allergy Clin Immunol. 2024. PMID: 38878020 Free PMC article.
SLE Antibody-Secreting Cells Are Characterized by Enhanced Peripheral Maturation and Survival Programs.
Chen W, Hong SH, Jenks SA, Anam FA, Tipton CM, Woodruff MC, Hom JR, Cashman KS, Faliti CE, Wang X, Kyu S, Wei C, Scharer CD, Mi T, Hicks S, Hartson L, Nguyen DC, Khosroshahi A, Lee S, Wang Y, Bugrovsky R, Ishii Y, Lee FE, Sanz I. Chen W, et al. Among authors: kyu s. Res Sq [Preprint]. 2023 Jun 27:rs.3.rs-3016327. doi: 10.21203/rs.3.rs-3016327/v1. Res Sq. 2023. Update in: Nat Commun. 2024 Mar 1;15(1):1899. doi: 10.1038/s41467-024-46053-w. PMID: 37461641 Free PMC article. Updated. Preprint.
Dysregulated naive B cells and de novo autoreactivity in severe COVID-19.
Woodruff MC, Ramonell RP, Haddad NS, Anam FA, Rudolph ME, Walker TA, Truong AD, Dixit AN, Han JE, Cabrera-Mora M, Runnstrom MC, Bugrovsky R, Hom J, Connolly EC, Albizua I, Javia V, Cashman KS, Nguyen DC, Kyu S, Singh Saini A, Piazza M, Tipton CM, Khosroshahi A, Gibson G, Martin GS, Maier CL, Esper A, Jenks SA, Lee FE, Sanz I. Woodruff MC, et al. Among authors: kyu s. Nature. 2022 Nov;611(7934):139-147. doi: 10.1038/s41586-022-05273-0. Epub 2022 Aug 31. Nature. 2022. PMID: 36044993 Free PMC article.
Single-cell analysis of human nasal mucosal IgE antibody secreting cells reveals a newly minted phenotype.
Ramonell RP, Brown M, Woodruff MC, Levy JM, Wise SK, DelGaudio J, Duan M, Saney CL, Kyu S, Cashman KS, Hom JR, Fucile CF, Rosenberg AF, Tipton CM, Sanz I, Gibson GC, Lee FE. Ramonell RP, et al. Among authors: kyu s. Mucosal Immunol. 2023 Jun;16(3):287-301. doi: 10.1016/j.mucimm.2023.02.008. Epub 2023 Mar 15. Mucosal Immunol. 2023. PMID: 36931600 Free PMC article.
Differential transcriptome and development of human peripheral plasma cell subsets.
Garimalla S, Nguyen DC, Halliley JL, Tipton C, Rosenberg AF, Fucile CF, Saney CL, Kyu S, Kaminski D, Qian Y, Scheuermann RH, Gibson G, Sanz I, Lee FE. Garimalla S, et al. Among authors: kyu s. JCI Insight. 2019 May 2;4(9):e126732. doi: 10.1172/jci.insight.126732. eCollection 2019 May 2. JCI Insight. 2019. PMID: 31045577 Free PMC article.
One-Stop Serum Assay Identifies COVID-19 Disease Severity and Vaccination Responses.
Haddad NS, Nguyen DC, Kuruvilla ME, Morrison-Porter A, Anam F, Cashman KS, Ramonell RP, Kyu S, Saini AS, Cabrera-Mora M, Derrico A, Alter D, Roback JD, Horwath M, O'Keefe JB, Wu HM, Wong AI, Dretler AW, Gripaldo R, Lane AN, Wu H, Chu HY, Lee S, Hernandez M, Engineer V, Varghese J, Patel R, Jalal A, French V, Guysenov I, Lane CE, Mengistsu T, Normile KE, Mnzava O, Le S, Sanz I, Daiss JL, Lee FE. Haddad NS, et al. Among authors: kyu s. Immunohorizons. 2021 May 17;5(5):322-335. doi: 10.4049/immunohorizons.2100011. Immunohorizons. 2021. PMID: 34001652 Free PMC article.
Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19.
Woodruff MC, Ramonell RP, Nguyen DC, Cashman KS, Saini AS, Haddad NS, Ley AM, Kyu S, Howell JC, Ozturk T, Lee S, Suryadevara N, Case JB, Bugrovsky R, Chen W, Estrada J, Morrison-Porter A, Derrico A, Anam FA, Sharma M, Wu HM, Le SN, Jenks SA, Tipton CM, Staitieh B, Daiss JL, Ghosn E, Diamond MS, Carnahan RH, Crowe JE Jr, Hu WT, Lee FE, Sanz I. Woodruff MC, et al. Among authors: kyu s. Nat Immunol. 2020 Dec;21(12):1506-1516. doi: 10.1038/s41590-020-00814-z. Epub 2020 Oct 7. Nat Immunol. 2020. PMID: 33028979 Free PMC article.
37 results