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Page 1
A phase IIb, open-label, randomized controlled dose ranging multi-centre trial to evaluate the safety, tolerability, pharmacokinetics and exposure-response relationship of different doses of delpazolid in combination with bedaquiline delamanid moxifloxacin in adult subjects with newly diagnosed, uncomplicated, smear-positive, drug-sensitive pulmonary tuberculosis.
Dierig A, Hoelscher M, Schultz S, Hoffmann L, Jarchow-MacDonald A, Svensson EM, Te Brake L, Aarnoutse R, Boeree M, McHugh TD, Wildner LM, Gong X, Phillips P, Minja LT, Ntinginya N, Mpagama S, Liyoyo A, Wallis RS, Sebe M, Mhimbira FA, Mbeya B, Rassool M, Geiter L, Cho YL, Heinrich N. Dierig A, et al. Among authors: liyoyo a. Trials. 2023 Jun 6;24(1):382. doi: 10.1186/s13063-023-07354-5. Trials. 2023. PMID: 37280643 Free PMC article. Clinical Trial.
Effect of seven anti-tuberculosis treatment regimens on sputum microbiome: a retrospective analysis of the HIGHRIF study 2 and PanACEA MAMS-TB clinical trials.
Musisi E, Wyness A, Eldirdiri S, Dombay E, Mtafya B, Ntinginya NE, Heinrich N, Kibiki GS, Hoelscher M, Boeree M, Aarnoutse R, Gillespie SH, Sabiiti W; PanACEA consortium. Musisi E, et al. Lancet Microbe. 2023 Nov;4(11):e913-e922. doi: 10.1016/S2666-5247(23)00191-X. Epub 2023 Oct 10. Lancet Microbe. 2023. PMID: 37832571 Free article.
Early empiric anti-Mycobacterium tuberculosis therapy for sepsis in sub-Saharan Africa: a protocol of a randomised clinical trial.
Said B, Nuwagira E, Liyoyo A, Arinaitwe R, Gitige C, Mushagara R, Buzaare P, Chongolo A, Jjunju S, Twesigye P, Boulware DR, Conaway M, Null M, Thomas TA, Heysell SK, Moore CC, Muzoora C, Mpagama SG. Said B, et al. Among authors: liyoyo a. BMJ Open. 2022 Jun 6;12(6):e061953. doi: 10.1136/bmjopen-2022-061953. BMJ Open. 2022. PMID: 35667721 Free PMC article.
Protocol for a feasibility randomized controlled trial to evaluate the efficacy, safety and tolerability of N-acetylcysteine in reducing adverse drug reactions among adults treated for multidrug-resistant tuberculosis in Tanzania.
Mpagama SG, Mvungi HC, Mbelele PM, Semvua HH, Liyoyo AA, de Guex KP, Sloan D, Kibiki GS, Boeree M, Phillips PPJ, Heysell SK. Mpagama SG, et al. Among authors: liyoyo aa. Pilot Feasibility Stud. 2023 Apr 1;9(1):55. doi: 10.1186/s40814-023-01281-7. Pilot Feasibility Stud. 2023. PMID: 37005695 Free PMC article.
Four-month moxifloxacin-based regimens for drug-sensitive tuberculosis.
Gillespie SH, Crook AM, McHugh TD, Mendel CM, Meredith SK, Murray SR, Pappas F, Phillips PP, Nunn AJ; REMoxTB Consortium. Gillespie SH, et al. N Engl J Med. 2014 Oct 23;371(17):1577-87. doi: 10.1056/NEJMoa1407426. Epub 2014 Sep 7. N Engl J Med. 2014. PMID: 25196020 Free PMC article. Clinical Trial.
Qualitative assessment of the impact of socioeconomic and cultural barriers on uptake and utilisation of tuberculosis diagnostic and treatment tools in East Africa: a cross-sectional study.
Msoka EF, Orina F, Sanga ES, Miheso B, Mwanyonga S, Meme H, Kiula K, Liyoyo A, Mwebaza I, Aturinde A, Joloba M, Mmbaga B, Amukoye E, Ntinginya NE, Gillespie SH, Sabiiti W. Msoka EF, et al. Among authors: liyoyo a. BMJ Open. 2021 Jul 12;11(7):e050911. doi: 10.1136/bmjopen-2021-050911. BMJ Open. 2021. PMID: 34253677 Free PMC article.
Unlocking the health system barriers to maximise the uptake and utilisation of molecular diagnostics in low-income and middle-income country setting.
Ntinginya NE, Kuchaka D, Orina F, Mwebaza I, Liyoyo A, Miheso B, Aturinde A, Njeleka F, Kiula K, Msoka EF, Meme H, Sanga E, Mwanyonga S, Olomi W, Minja L, Joloba M, Mmbaga BT, Amukoye E, Gillespie SH, Sabiiti W. Ntinginya NE, et al. Among authors: liyoyo a. BMJ Glob Health. 2021 Aug;6(8):e005357. doi: 10.1136/bmjgh-2021-005357. BMJ Glob Health. 2021. PMID: 34429298 Free PMC article.
13 results