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2020 2
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18 results

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Page 1
A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease.
Wightman DP, Jansen IE, Savage JE, Shadrin AA, Bahrami S, Holland D, Rongve A, Børte S, Winsvold BS, Drange OK, Martinsen AE, Skogholt AH, Willer C, Bråthen G, Bosnes I, Nielsen JB, Fritsche LG, Thomas LF, Pedersen LM, Gabrielsen ME, Johnsen MB, Meisingset TW, Zhou W, Proitsi P, Hodges A, Dobson R, Velayudhan L, Heilbron K, Auton A; 23andMe Research Team; Sealock JM, Davis LK, Pedersen NL, Reynolds CA, Karlsson IK, Magnusson S, Stefansson H, Thordardottir S, Jonsson PV, Snaedal J, Zettergren A, Skoog I, Kern S, Waern M, Zetterberg H, Blennow K, Stordal E, Hveem K, Zwart JA, Athanasiu L, Selnes P, Saltvedt I, Sando SB, Ulstein I, Djurovic S, Fladby T, Aarsland D, Selbæk G, Ripke S, Stefansson K, Andreassen OA, Posthuma D. Wightman DP, et al. Nat Genet. 2021 Sep;53(9):1276-1282. doi: 10.1038/s41588-021-00921-z. Epub 2021 Sep 7. Nat Genet. 2021. PMID: 34493870 Free PMC article.
Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders.
Eijsbouts C, Zheng T, Kennedy NA, Bonfiglio F, Anderson CA, Moutsianas L, Holliday J, Shi J, Shringarpure S; 23andMe Research Team; Voda AI; Bellygenes Initiative; Farrugia G, Franke A, Hübenthal M, Abecasis G, Zawistowski M, Skogholt AH, Ness-Jensen E, Hveem K, Esko T, Teder-Laving M, Zhernakova A, Camilleri M, Boeckxstaens G, Whorwell PJ, Spiller R, McVean G, D'Amato M, Jostins L, Parkes M. Eijsbouts C, et al. Nat Genet. 2021 Nov;53(11):1543-1552. doi: 10.1038/s41588-021-00950-8. Epub 2021 Nov 5. Nat Genet. 2021. PMID: 34741163 Free PMC article.
Genetic determinants of daytime napping and effects on cardiometabolic health.
Dashti HS, Daghlas I, Lane JM, Huang Y, Udler MS, Wang H, Ollila HM, Jones SE, Kim J, Wood AR; 23andMe Research Team; Weedon MN, Aslibekyan S, Garaulet M, Saxena R. Dashti HS, et al. Nat Commun. 2021 Feb 10;12(1):900. doi: 10.1038/s41467-020-20585-3. Nat Commun. 2021. PMID: 33568662 Free PMC article.
The Genetic Architecture of Depression in Individuals of East Asian Ancestry: A Genome-Wide Association Study.
Giannakopoulou O, Lin K, Meng X, Su MH, Kuo PH, Peterson RE, Awasthi S, Moscati A, Coleman JRI, Bass N, Millwood IY, Chen Y, Chen Z, Chen HC, Lu ML, Huang MC, Chen CH, Stahl EA, Loos RJF, Mullins N, Ursano RJ, Kessler RC, Stein MB, Sen S, Scott LJ, Burmeister M, Fang Y, Tyrrell J, Jiang Y, Tian C, McIntosh AM, Ripke S, Dunn EC, Kendler KS, Walters RG, Lewis CM, Kuchenbaecker K; 23andMe Research Team, China Kadoorie Biobank Collaborative Group, and Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Giannakopoulou O, et al. JAMA Psychiatry. 2021 Nov 1;78(11):1258-1269. doi: 10.1001/jamapsychiatry.2021.2099. JAMA Psychiatry. 2021. PMID: 34586374 Free PMC article.
Multitrait genetic association analysis identifies 50 new risk loci for gastro-oesophageal reflux, seven new loci for Barrett's oesophagus and provides insights into clinical heterogeneity in reflux diagnosis.
Ong JS, An J, Han X, Law MH, Nandakumar P; 23andMe Research team; Esophageal cancer consortium; Schumacher J, Gockel I, Bohmer A, Jankowski J, Palles C, Olsen CM, Neale RE, Fitzgerald R, Thrift AP, Vaughan TL, Buas MF, Hinds DA, Gharahkhani P, Kendall BJ, MacGregor S. Ong JS, et al. Gut. 2022 Jun;71(6):1053-1061. doi: 10.1136/gutjnl-2020-323906. Epub 2021 Jun 29. Gut. 2022. PMID: 34187846 Free PMC article.
Hemorrhagic transformation in acute ischemic stroke: hemorrhagic subtypes and symptomatic intracranial hemorrhage.
Luff MK, Khezri N, Miralbes S, Naravetla B, Spiotta AM, Loehr C, Martínez-Galdámez M, McTaggart RA, Defreyne L, Vega P, Zaidat OO, Price LL, Gupta R, Möhlenbruch MA, Liebeskind DS; ASSIST Investigators. Luff MK, et al. J Neurointerv Surg. 2024 Jul 5:jnis-2024-021725. doi: 10.1136/jnis-2024-021725. Online ahead of print. J Neurointerv Surg. 2024. PMID: 38969497
Genetic analyses identify widespread sex-differential participation bias.
Pirastu N, Cordioli M, Nandakumar P, Mignogna G, Abdellaoui A, Hollis B, Kanai M, Rajagopal VM, Parolo PDB, Baya N, Carey CE, Karjalainen J, Als TD, Van der Zee MD, Day FR, Ong KK; FinnGen Study; 23andMe Research Team; iPSYCH Consortium; Morisaki T, de Geus E, Bellocco R, Okada Y, Børglum AD, Joshi P, Auton A, Hinds D, Neale BM, Walters RK, Nivard MG, Perry JRB, Ganna A. Pirastu N, et al. Nat Genet. 2021 May;53(5):663-671. doi: 10.1038/s41588-021-00846-7. Epub 2021 Apr 22. Nat Genet. 2021. PMID: 33888908 Free PMC article.
18 results