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Lumacaftor/ivacaftor therapy fails to increase insulin secretion in F508del/F508del CF patients.
Moheet A, Beisang D, Zhang L, Sagel SD, VanDalfsen JM, Heltshe SL, Frederick C, Mann M, Antos N, Billings J, Rowe SM, Moran A; PROSPECT Investigators of the Cystic Fibrosis Foundation Therapeutics Development Network. Moheet A, et al. J Cyst Fibros. 2021 Mar;20(2):333-338. doi: 10.1016/j.jcf.2020.09.001. Epub 2020 Sep 8. J Cyst Fibros. 2021. PMID: 32917547 Free PMC article.