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Page 1
Asciminib in Newly Diagnosed Chronic Myeloid Leukemia.
Hochhaus A, Wang J, Kim DW, Kim DDH, Mayer J, Goh YT, le Coutre P, Takahashi N, Kim I, Etienne G, Andorsky D, Issa GC, Larson RA, Bombaci F, Kapoor S, McCulloch T, Malek K, Yau L, Ifrah S, Hoch M, Cortes JE, Hughes TP; ASC4FIRST Investigators. Hochhaus A, et al. N Engl J Med. 2024 Sep 12;391(10):885-898. doi: 10.1056/NEJMoa2400858. Epub 2024 May 31. N Engl J Med. 2024. PMID: 38820078 Clinical Trial.
Accelerated-phase CML: de novo and transformed.
Shanmuganathan N, Hughes TP. Shanmuganathan N, et al. Hematology Am Soc Hematol Educ Program. 2023 Dec 8;2023(1):459-468. doi: 10.1182/hematology.2023000446. Hematology Am Soc Hematol Educ Program. 2023. PMID: 38066863 Free PMC article.
A Phase 3 Trial of Luspatercept in Patients with Transfusion-Dependent β-Thalassemia.
Cappellini MD, Viprakasit V, Taher AT, Georgiev P, Kuo KHM, Coates T, Voskaridou E, Liew HK, Pazgal-Kobrowski I, Forni GL, Perrotta S, Khelif A, Lal A, Kattamis A, Vlachaki E, Origa R, Aydinok Y, Bejaoui M, Ho PJ, Chew LP, Bee PC, Lim SM, Lu MY, Tantiworawit A, Ganeva P, Gercheva L, Shah F, Neufeld EJ, Thompson A, Laadem A, Shetty JK, Zou J, Zhang J, Miteva D, Zinger T, Linde PG, Sherman ML, Hermine O, Porter J, Piga A; BELIEVE Investigators. Cappellini MD, et al. N Engl J Med. 2020 Mar 26;382(13):1219-1231. doi: 10.1056/NEJMoa1910182. N Engl J Med. 2020. PMID: 32212518 Clinical Trial.
Asciminib monotherapy in patients with CML-CP without BCR::ABL1 T315I mutations treated with at least two prior TKIs: 4-year phase 1 safety and efficacy results.
Mauro MJ, Hughes TP, Kim DW, Rea D, Cortes JE, Hochhaus A, Sasaki K, Breccia M, Talpaz M, Ottmann O, Minami H, Goh YT, DeAngelo DJ, Heinrich MC, Gómez-García de Soria V, le Coutre P, Mahon FX, Janssen JJWM, Deininger M, Shanmuganathan N, Geyer MB, Cacciatore S, Polydoros F, Agrawal N, Hoch M, Lang F. Mauro MJ, et al. Among authors: shanmuganathan n. Leukemia. 2023 May;37(5):1048-1059. doi: 10.1038/s41375-023-01860-w. Epub 2023 Mar 22. Leukemia. 2023. PMID: 36949155 Free PMC article. Clinical Trial.
Early Management of CML.
Shanmuganathan N, Hughes TP. Shanmuganathan N, et al. Curr Hematol Malig Rep. 2019 Dec;14(6):480-491. doi: 10.1007/s11899-019-00550-8. Curr Hematol Malig Rep. 2019. PMID: 31701368 Review.
Management of TKI-resistant chronic phase CML.
Hughes TP, Shanmuganathan N. Hughes TP, et al. Among authors: shanmuganathan n. Hematology Am Soc Hematol Educ Program. 2022 Dec 9;2022(1):129-137. doi: 10.1182/hematology.2022000328. Hematology Am Soc Hematol Educ Program. 2022. PMID: 36485117 Free PMC article. Review.
Asciminib monotherapy as frontline treatment of chronic-phase chronic myeloid leukemia: results from the ASCEND study.
Yeung DT, Shanmuganathan N, Reynolds J, Branford S, Walia M, Yong ASM, Shortt J, Chee L, Viiala N, Cunningham I, Ross DM, D'Souza A, Wright M, Harrup R, Forsyth C, Filshie R, Lane S, Browett P, Grove C, Grigg AP, Hughes TP. Yeung DT, et al. Among authors: shanmuganathan n. Blood. 2024 Nov 7;144(19):1993-2001. doi: 10.1182/blood.2024024657. Blood. 2024. PMID: 39102630
Beyond BCR::ABL1-The Role of Genomic Analyses in the Management of CML.
Branford S, Fernandes A, Shahrin N, Maqsood M, Shanmuganathan N, Wadham C. Branford S, et al. Among authors: shanmuganathan n. J Natl Compr Canc Netw. 2024 Feb;22(1):e237335. doi: 10.6004/jnccn.2023.7335. J Natl Compr Canc Netw. 2024. PMID: 38394774 Review.
50 results