Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 2
1952 1
1954 1
1955 1
1956 2
1957 3
1958 2
1959 1
1960 1
1961 5
1962 1
1963 7
1964 12
1965 10
1966 9
1967 7
1968 17
1969 15
1970 15
1971 13
1972 25
1973 20
1974 33
1975 260
1976 261
1977 222
1978 207
1979 222
1980 202
1981 233
1982 262
1983 257
1984 286
1985 345
1986 393
1987 386
1988 477
1989 491
1990 600
1991 652
1992 713
1993 721
1994 774
1995 706
1996 713
1997 684
1998 679
1999 588
2000 619
2001 570
2002 544
2003 588
2004 539
2005 563
2006 347
2007 365
2008 344
2009 325
2010 309
2011 324
2012 338
2013 326
2014 360
2015 320
2016 299
2017 292
2018 291
2019 290
2020 251
2021 278
2022 284
2023 270
2024 170
2025 13

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

19,681 results

Results by year

Filters applied: . Clear all
Page 1
Showing results for tropanes p
Search for Tiopanas P instead (1 results)
(-)-Norcocaine.
Zhu N, Reynolds M, Klein CL, Trudell M. Zhu N, et al. Acta Crystallogr C. 1994 Dec 15;50 ( Pt 12):2067-9. doi: 10.1107/s0108270194003367. Acta Crystallogr C. 1994. PMID: 7848613
The title compound, [2R,3S-(2 beta,3 beta)]-methyl 3-(benzoyloxy)-8-azabicyclo[3.2.1]octane-2-carboxylate, C16H19NO4, is a metabolite of the tropane alkaloid cocaine. The molecule crystallized as the free base with the piperidine ring in a chair conformation. The tropan …
The title compound, [2R,3S-(2 beta,3 beta)]-methyl 3-(benzoyloxy)-8-azabicyclo[3.2.1]octane-2-carboxylate, C16H19NO4, is a metabolite of the …
Triple monoamine uptake inhibitors.
Capelli AM, Micheli F. Capelli AM, et al. Pharm Pat Anal. 2012 Sep;1(4):469-81. doi: 10.4155/ppa.12.46. Pharm Pat Anal. 2012. PMID: 24236884 Review.
Glymphatic function assessment in Parkinson's disease using diffusion tensor image analysis along the perivascular space.
Bae YJ, Kim JM, Choi BS, Choi JH, Ryoo N, Song YS, Cho SJ, Kim JH. Bae YJ, et al. Parkinsonism Relat Disord. 2023 Sep;114:105767. doi: 10.1016/j.parkreldis.2023.105767. Epub 2023 Jul 26. Parkinsonism Relat Disord. 2023. PMID: 37523953 Free article.

The ALPS-index was lower in the PD group than in the controls (1.51 0.22 versus 1.66 0.20; P < 0.001). In the PD group, the ALPS-index negatively correlated with the UPDRS-III score (r = -0.526), and positively correlated with the MMSE (r = 0.377) and MoCA scores (r = 0

…

The ALPS-index was lower in the PD group than in the controls (1.51 0.22 versus 1.66 0.20; P < 0.001). In the PD group, the ALPS-i

…
The Role of Dual-Phase 18 F-FP-CIT PET to Early Diagnosis of Corticobasal Syndrome.
Kim MS, Park DG, Shin IJ, An YS, Yoon JH. Kim MS, et al. Clin Nucl Med. 2024 Feb 1;49(2):124-130. doi: 10.1097/RLU.0000000000004979. Epub 2023 Nov 25. Clin Nucl Med. 2024. PMID: 38015725

Striatal DAT uptake (delayed phase) revealed that the caudate showed lower SUVR and prominent asymmetry in the CBS group, and the caudate-to-putamen ratio (CP ratio) was significantly lower in CBS patients ( P < 0.001). Among the parameters (early and delayed), the CP r

…
Striatal DAT uptake (delayed phase) revealed that the caudate showed lower SUVR and prominent asymmetry in the CBS group, and the caudate-to …
Prolonged dopamine and serotonin transporter inhibition after exposure to tropanes.
Bennett BA, Hollingsworth CK, Martin RS, Childers SR, Ehrenkaufer RE, Porrino LJ, Davies HM. Bennett BA, et al. Neuropharmacology. 1998;37(1):123-30. doi: 10.1016/s0028-3908(97)00194-9. Neuropharmacology. 1998. PMID: 9680265
Cocaine and tropane analogs are known to interact with biogenic monoamine transporters by inhibiting amine uptake. Previous in vivo studies have demonstrated that some of these tropanes produce a longer lasting behavioral effect compared with cocaine. We have previo …
Cocaine and tropane analogs are known to interact with biogenic monoamine transporters by inhibiting amine uptake. Previous in vivo s …
Synthesis, ligand binding, and quantitative structure-activity relationship study of 3 beta-(4'-substituted phenyl)-2 beta-heterocyclic tropanes: evidence for an electrostatic interaction at the 2 beta-position.
Kotian P, Mascarella SW, Abraham P, Lewin AH, Boja JW, Kuhar MJ, Carroll FI. Kotian P, et al. J Med Chem. 1996 Jul 5;39(14):2753-63. doi: 10.1021/jm960160e. J Med Chem. 1996. PMID: 8709106
A set of 3 beta-(4'-substituted phenyl)-2 beta-heterocyclic tropanes was designed, synthesized, and characterized. We discovered that these compounds can function as bioisosteric replacements for the corresponding WIN 35,065-2 analogs which possess a 2 beta-carbomethoxy gr …
A set of 3 beta-(4'-substituted phenyl)-2 beta-heterocyclic tropanes was designed, synthesized, and characterized. We discovered that …
Structure-activity relationship comparison of (S)-2beta-substituted 3alpha-(bis[4-fluorophenyl]methoxy)tropanes and (R)-2beta-substituted 3beta-(3,4-dichlorophenyl)tropanes at the dopamine transporter.
Zou MF, Kopajtic T, Katz JL, Newman AH. Zou MF, et al. J Med Chem. 2003 Jul 3;46(14):2908-16. doi: 10.1021/jm0300375. J Med Chem. 2003. PMID: 12825932
Extensive structure-activity relationships at the dopamine transporter (DAT) have been developed around two classes of tropane-based ligands. Opposing stereoselectivity and divergent structural requirements for optimal DAT binding suggest that these tropane-based DA …
Extensive structure-activity relationships at the dopamine transporter (DAT) have been developed around two classes of tropane-based …
Efficacy and safety of aclidinium/formoterol versus monotherapies and aclidinium versus placebo in Chinese and other Asian patients with moderate-to-severe COPD: The AVANT Phase 3 study.
Sun Y, Molins E, Daoud SZ, Trivedi R, Stewart C, Lamarca R, Bharali P, Garcia-Gil E. Sun Y, et al. Respir Med. 2023 Nov;218:107393. doi: 10.1016/j.rmed.2023.107393. Epub 2023 Aug 26. Respir Med. 2023. PMID: 37640273 Free article. Clinical Trial.

At Week 24, aclidinium/formoterol demonstrated improvements from baseline in 1-h morning post-dose forced expiratory volume in 1 s (FEV(1)) vs aclidinium (least squares [LS] mean 92 mL; 95% confidence interval [CI] 60, 124 mL; p < 0.001), and in trough FEV(1) vs formote

…
At Week 24, aclidinium/formoterol demonstrated improvements from baseline in 1-h morning post-dose forced expiratory volume in 1 s (FEV(1)) …
Tc-99m-labeled tropanes as dopamine transporter imaging agents.
Meegalla S, Plössl K, Kung MP, Chumpradit S, Stevenson DA, Frederick D, Kung HF. Meegalla S, et al. Bioconjug Chem. 1996 Jul-Aug;7(4):421-9. doi: 10.1021/bc960029l. Bioconjug Chem. 1996. PMID: 8853455
The development of novel Tc-9m-labeled tropane derivatives as dopamine transporter imaging agents is reported. A series of neutral and lipophilic conjugated complexes, containing N-(alkylthiolato)-tropane, aminobis(ethylthiolato), and a [99mTc]TcO3+ center core, wer …
The development of novel Tc-9m-labeled tropane derivatives as dopamine transporter imaging agents is reported. A series of neutral an …
19,681 results
You have reached the last available page of results. Please see the User Guide for more information.