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Clinical and human leucocyte antigen class II haplotype associations of autoantibodies to small ubiquitin-like modifier enzyme, a dermatomyositis-specific autoantigen target, in UK Caucasian adult-onset myositis.
Betteridge ZE, Gunawardena H, Chinoy H, North J, Ollier WE, Cooper RG, McHugh NJ; UK Adult Onset Myositis Immunogenetic Collaboration. Betteridge ZE, et al. Ann Rheum Dis. 2009 Oct;68(10):1621-5. doi: 10.1136/ard.2008.097162. Epub 2008 Oct 17. Ann Rheum Dis. 2009. PMID: 18930994
In adult onset myositis, the presence of interstitial lung disease and myositis specific/associated antibodies are governed by HLA class II haplotype, rather than by myositis subtype.
Chinoy H, Salway F, Fertig N, Shephard N, Tait BD, Thomson W, Isenberg DA, Oddis CV, Silman AJ, Ollier WE, Cooper RG; UK Adult Onset Myositis Immunogenetic Collaboration (AOMIC). Chinoy H, et al. Arthritis Res Ther. 2006;8(1):R13. doi: 10.1186/ar1862. Arthritis Res Ther. 2006. PMID: 16507114 Free PMC article.
Tumour necrosis factor-alpha single nucleotide polymorphisms are not independent of HLA class I in UK Caucasians with adult onset idiopathic inflammatory myopathies.
Chinoy H, Salway F, John S, Fertig N, Tait BD, Oddis CV, Ollier WE, Cooper RG; UK Adult Onset Myositis Immunogenetic Collaboration (AOMIC). Chinoy H, et al. Rheumatology (Oxford). 2007 Sep;46(9):1411-6. doi: 10.1093/rheumatology/kem145. Epub 2007 Jun 22. Rheumatology (Oxford). 2007. PMID: 17586554
The protein tyrosine phosphatase N22 gene is associated with juvenile and adult idiopathic inflammatory myopathy independent of the HLA 8.1 haplotype in British Caucasian patients.
Chinoy H, Platt H, Lamb JA, Betteridge Z, Gunawardena H, Fertig N, Varsani H, Davidson J, Oddis CV, McHugh NJ, Wedderburn LR, Ollier WE, Cooper RG; UK Adult Onset Myositis Immunogenetic Collaboration and the Juvenile Dermatomyositis Research Group. Chinoy H, et al. Arthritis Rheum. 2008 Oct;58(10):3247-54. doi: 10.1002/art.23900. Arthritis Rheum. 2008. PMID: 18821667 Free PMC article.
HLA-DPB1 associations differ between DRB1*03 positive anti-Jo-1 and anti-PM-Scl antibody positive idiopathic inflammatory myopathy.
Chinoy H, Payne D, Poulton KV, Fertig N, Betteridge Z, Gunawardena H, Davidson JE, Oddis CV, McHugh NJ, Wedderburn LR, Ollier WE, Cooper RG; UK Adult Onset Myositis Immunogenetic Collaboration & UK Juvenile Dermatomyositis Research Group. Chinoy H, et al. Rheumatology (Oxford). 2009 Oct;48(10):1213-7. doi: 10.1093/rheumatology/kep248. Epub 2009 Aug 18. Rheumatology (Oxford). 2009. PMID: 19690132