01/6​How breakups can change brain chemistry, as per science

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Have you ever wondered why people experience such strong emotions after a breakup? Why is it challenging to move on from someone who wasn't a significant part of your life for long before the relationship started? Have you ever thought about why people often lose motivation and find it difficult to connect with new potential partners after a breakup?



Below, you'll find answers to these and other important questions. Keep reading to explore interesting insights and facts about breakups and how they influence changes in brain chemistry. by TOI Lifestyle Deskreadmore

02/6​Stress response

​Stress response
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A breakup is always a challenging and uncomfortable experience to go through. It can significantly trigger your stress levels, as your body reacts by releasing a hormone called cortisol. When overproduced, this hormone can disrupt your brain function. Chronic stress from a breakup can make you feel more anxious, sad, and depressed than usual, affecting every aspect of your life, from the quality of your sleep to your emotions and work.

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03/6​Reward system

​Reward system
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Romantic love activates your brain's reward system by releasing chemicals known as neurotransmitters, such as dopamine and oxytocin. These chemicals are crucial for helping you relax and promoting feelings of happiness and connection.

During a breakup, when there's a sudden dip in these chemicals, it can make you feel deeply anxious and like something significant is missing. This feeling can be quite intense, similar to experiencing a drug withdrawal. It can lead to feelings of sadness and anxiety, and make it difficult to focus or find pleasure in activities that you once enjoyed. This emotional challenge can continue for days, weeks, or even months.

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04/6​Attachment systems

​Attachment systems
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During a breakup, significant changes occur in parts of your brain that are connected to how you feel attached to someone. Two important regions are the anterior cingulate cortex (ACC) and the insula, which become active during this time.



The ACC is essential for processing emotional pain and regulating emotions. It helps you manage your emotional responses to different situations, including the sadness associated with a breakup. The insula is involved in various emotional functions, such as self-awareness and empathy, and plays a role in recognizing and interpreting emotions from oneself and others.

During a breakup, the insula may also become activated as it processes the emotional impact of the relationship ending and adjusts to the new emotional circumstances. Together, these brain parts play a significant role in processing the attachment bond that has been damaged, resulting in feelings of loss, sadness, and sometimes physical sensations of heartache. This is the reason why some people experience intense emotions during this period.readmore

05/6Impact on self-concept

Impact on self-concept
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People going through a breakup can change the way they perceive themselves. During this time, individuals might start feeling differently about their own value and begin to question their self-worth. This can significantly impact their self-esteem and confidence, as they may question what they deserve and what they don't. These changes can further influence brain function, affecting their ability to effectively manage their emotions.readmore

06/6Changes in Neuroplasticity

Changes in Neuroplasticity
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Neuroplasticity means the brain's ability to change and adapt by forming new connections between nerve cells. When you go through a breakup, the emotional stress and changes in brain chemicals can significantly affect and disrupt this process. These changes in neuroplasticity can impact how your brain handles emotions. It might make it harder to recover emotionally from the breakup and affect how resilient you feel in the long run. Essentially, it's about how flexible your brain is in coping with and recovering from difficult emotional challenges like a breakup.readmore