Yield of fluid-attenuated inversion recovery in drug-resistant focal epilepsy with noninformative conventional magnetic resonance imaging

Eur Neurol. 1999;41(2):64-72. doi: 10.1159/000008005.

Abstract

Purpose: To determine the role in presurgical assessment and evaluate the yield of fast fluid-attenuated inversion recovery (FLAIR) sequences for patients with intractable partial epilepsy for whom conventional magnetic resonance imaging (MRI) was normal.

Material and methods: Forty patients were selected. Conventional MRI including spin echo T1-weighted sagittal images and fast spin echo T2-weighted axial images was normal in 33 patients and showed noninformative lesions in 7. Fast FLAIR and T2-weighted sequences were performed perpendicularly to the hippocampal long axis.

Results: Additional abnormalities were found in 40%. They were correlated with electroclinical data in 13 patients (32.5%) and not correlated or doubtful in 3 (7.5%).

Conclusion: Fast FLAIR sequences brought congruent additional information in 32.5% cases and seemed useful in presurgical evaluation.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Brain / pathology*
  • Brain / surgery
  • Cerebrospinal Fluid / physiology*
  • Drug Resistance
  • Electroencephalography
  • Epilepsies, Partial / diagnosis*
  • Epilepsies, Partial / drug therapy*
  • Epilepsies, Partial / surgery
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Retrospective Studies