Successful donation and transplantation of multiple organs after fatal poisoning with brodifacoum, a long-acting anticoagulant rodenticide: case report

Transplantation. 1999 Feb 15;67(3):475-8. doi: 10.1097/00007890-199902150-00022.

Abstract

Background: Successful organ donation has been reported after death from poisonings with cyanide, carbon monoxide, methanol, benzodiazepines, and tricyclic antidepressants. In this report, we describe a case of multiple organ donation from a previously healthy individual who died from poisoning with the long-acting anticoagulant rodenticide, brodifacoum.

Methods: Case report and review of the literature.

Results: All organs procured from the poisoned donor functioned adequately, and there were no hemorrhagic complications in any of the recipients.

Conclusion: This case demonstrates that brodifacoum poisoning is not an absolute contraindication to organ donation from brain-dead patients who have sustained a fatal ingestion.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • 4-Hydroxycoumarins / poisoning*
  • Adult
  • Anticoagulants / poisoning*
  • Corneal Transplantation
  • Fatal Outcome
  • Female
  • Heart Transplantation
  • Humans
  • Kidney Transplantation
  • Liver Transplantation
  • Lung Transplantation
  • Male
  • Middle Aged
  • Organ Transplantation*
  • Pancreas Transplantation
  • Poisoning*
  • Suicide
  • Tissue Donors*

Substances

  • 4-Hydroxycoumarins
  • Anticoagulants
  • bromfenacoum