[Morphometric features in the lamina cribrosa observed by a scanning laser ophthalmoscope]

Nippon Ganka Gakkai Zasshi. 1999 Jan;103(1):48-55.
[Article in Japanese]

Abstract

Purpose: We describe a method for the morphometric analysis of the pores in the lamina cribrosa using a confocal scanning laser ophthalmoscope (SLO: Rodenstock company, Germany).

Methods: Four eyes with glaucoma and four eyes with non-glaucoma patients were examined. Sixteen consecutive images were acquired from the surface of the retina to the bottom of the optic disc excavation with +0.25 diopter increments by a He-Ne laser (633 nm) under 20 degree field of view. The images from each section were processed and combined with the aid of Macintosh software.

Results: Eyes with physiological cupping showed uniformly round or elliptical pores, whereas compressed and elongated pores were frequently encountered in eyes with primary open angle glaucoma (POAG).

Conclusion: The technique described allows, in vivo morphometry of the surface of the internal lamina cribrosa and was considered to be useful to evaluate glaucomatous progression.

Publication types

  • English Abstract

MeSH terms

  • Glaucoma / pathology*
  • Humans
  • Microscopy, Confocal*
  • Models, Biological
  • Ophthalmoscopy*
  • Optic Disk / pathology*