Chick Barx2b, a marker for myogenic cells also expressed in branchial arches and neural structures

Mech Dev. 1999 Feb;80(2):203-6. doi: 10.1016/s0925-4773(98)00216-0.

Abstract

We have isolated a new chicken gene, cBarx2b, which is related to mBarx2 in sequence, although the expression patterns of the two genes are quite different from one another. The cBarx2b gene is expressed in craniofacial structures, regions of the neural tube, and muscle groups in the limb, neck and cloaca. Perturbation of anterior muscle pattern by application of Sonic Hedgehog protein results in a posteriorization of cBarx2b expression.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Biomarkers
  • Branchial Region / embryology*
  • Branchial Region / metabolism
  • Chick Embryo / metabolism*
  • Chick Embryo / ultrastructure
  • Chickens / genetics*
  • Cloaca / embryology
  • Cloaca / metabolism
  • DNA, Complementary / genetics
  • Ectoderm / metabolism
  • Extremities / embryology
  • Gene Expression Regulation, Developmental*
  • Hedgehog Proteins
  • Homeodomain Proteins / genetics
  • Homeodomain Proteins / physiology*
  • Mice / genetics
  • Molecular Sequence Data
  • Muscles / embryology
  • Muscles / metabolism
  • Nervous System / embryology*
  • Nervous System / metabolism
  • Protein Biosynthesis
  • Recombinant Fusion Proteins / biosynthesis
  • Sequence Alignment
  • Sequence Homology, Amino Acid
  • Somites / metabolism
  • Trans-Activators*

Substances

  • Barx2 protein, mouse
  • Biomarkers
  • DNA, Complementary
  • Hedgehog Proteins
  • Homeodomain Proteins
  • Recombinant Fusion Proteins
  • Trans-Activators

Associated data

  • GENBANK/AF102555