Sinus histiocytosis presenting as bilateral epibulbar masses

Am J Ophthalmol. 1999 Mar;127(3):360-1. doi: 10.1016/s0002-9394(98)00321-3.

Abstract

Purpose: To report a case of sinus histiocytosis presenting as multiple, bilateral epibulbar masses.

Methods: We examined a 4-year-old child with a 2-month history of gradually enlarging, salmon-colored epibulbar masses. Excisional biopsies and a systemic evaluation were performed.

Results: Systemic evaluation was normal; no lymphadenopathy was documented. Histopathologic evaluation disclosed features consistent with sinus histiocytosis. Flow cytometry and gene rearrangement studies confirmed the benign nature of the disease. No tumor recurrence was noted.

Conclusion: Sinus histiocytosis may present as isolated epibulbar masses that may be treated with surgical excision.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child, Preschool
  • Conjunctival Diseases / diagnosis*
  • Conjunctival Diseases / metabolism
  • Conjunctival Diseases / pathology
  • Female
  • Histiocytosis, Sinus / diagnosis*
  • Histiocytosis, Sinus / metabolism
  • Histiocytosis, Sinus / pathology
  • Humans
  • Immunohistochemistry
  • Lymphocytes / pathology
  • S100 Proteins / metabolism

Substances

  • S100 Proteins