In the present study the age-related changes of pQCT values in normal Polish women were examined. The volumetric bone mineral density, trabecular density, cortical density and Strength Strain Index was measured using peripheral quantitative computed tomography (Stratec XCT 960) in 459 healthy women aged 18-60 years. Bone mineral measurement of the distal and proximal radius may be useful in evaluation of age-related bone loss, fracture risk and for diagnosis of osteoporosis.