Tuberculous stenosis of the left main bronchus: results of treatment with balloons and metallic stents

J Vasc Interv Radiol. 1999 Mar;10(3):352-8. doi: 10.1016/s1051-0443(99)70042-4.

Abstract

Purpose: To assess the results of treatment with balloon dilation and metallic Z stents in patients with tuberculous stenosis of the left main bronchus.

Materials and methods: Nineteen patients with tuberculous stenosis of the left main bronchus were treated with balloon (n = 15) and self-expanding metallic Z stents (n = 4). Respiratory status and pulmonary function tests were followed up for 2-90 months.

Results: In the balloon group, improvements in dyspnea occurred in 73% (11 of 15 patients) immediately, 73% after 1 month, 73% after 6 months, 64% after 1 year, 64% after 3 years, and 42% after 6 years (Kaplan-Meier method). Improvement of pulmonary function (FEV1 or FVC) was achieved in 62% (eight of 13) after 1 year. In the stent group, immediate improvements of dyspnea or pulmonary function occurred in all patients. However, fracture of the stents occurred in two patients, at 4 and 18 months, respectively. Occlusion of the lumen of the stent by granulation tissue occurred in another at 18 months.

Conclusion: Balloon dilation can be an effective method for the treatment of tuberculous stenosis of the main bronchus. Metallic Z stents should be used cautiously because of their problems of mechanical durability and overgrowth of granulation tissue.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Bronchial Diseases / diagnosis
  • Bronchial Diseases / etiology
  • Bronchial Diseases / therapy*
  • Bronchography
  • Bronchoscopy
  • Catheterization*
  • Constriction, Pathologic
  • Dyspnea / diagnosis
  • Dyspnea / etiology
  • Dyspnea / therapy
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Respiratory Function Tests
  • Retrospective Studies
  • Stents*
  • Treatment Outcome
  • Tuberculosis, Pulmonary / complications*
  • Tuberculosis, Pulmonary / physiopathology