Angiography is the standard with which new methods of vascular imaging are compared. In this article, selected recent developments affecting the practice of angiography will be discussed. First, a brief review and update of contrast media for intravascular use will be presented. Second, principles and current methods of optimizing the diagnostic arteriogram will be covered with emphasis on the extremities and aorto-femoral angiography. Finally, some of the advantages, limitations, and the role of modern angiography will be discussed.