Amplatz guiding catheters have traditionally been recommended for performing Left Circumflex PTCA because of their enhanced support. The Voda (Scimed Inc.) design guiding catheter may provide similar support for the left coronary artery, particularly the left circumflex, with less catheter manipulation. We prospectively randomized 40 patients to either Amplatz or Voda guiding catheters to compare ease of use and observed that a Voda design guiding catheter has more favorable characteristics for use without sacrificing support.