Impairment of serotonin-mediated nitric oxide release across the coronary bed in patients with coronary spastic angina

Am J Cardiol. 1999 Mar 15;83(6):953-5, A9. doi: 10.1016/s0002-9149(98)01054-6.

Abstract

Simultaneous assessment of plasma nitrate/nitrite and serotonin levels revealed possible impairment of serotonin-mediated nitric oxide release in patients with coronary spastic angina.

MeSH terms

  • Aged
  • Angina Pectoris, Variant / metabolism*
  • Coronary Vessels / metabolism*
  • Endothelium, Vascular / metabolism
  • Female
  • Humans
  • Male
  • Middle Aged
  • Nitric Oxide / biosynthesis*
  • Nitric Oxide / blood
  • Serotonin / blood
  • Serotonin / physiology*

Substances

  • Nitric Oxide
  • Serotonin