Abstract
After oral or parenteral administration of chemotherapeutic agents, these drugs are transported to the tissues by the blood in different fractions: plasma water, plasma proteins or cells. In this review, the role of the red blood cell in storage, transport and metabolism of different anti-cancer drugs is described.
MeSH terms
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Administration, Oral
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Anthracyclines / blood
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Antibiotics, Antineoplastic / blood
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Antineoplastic Agents / blood*
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Antineoplastic Agents / pharmacokinetics
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Asparaginase / blood
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Asparaginase / pharmacokinetics
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Asparaginase / toxicity
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Doxorubicin / blood
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Epirubicin / blood
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Erythrocytes / drug effects
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Erythrocytes / metabolism*
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Fluorouracil / blood
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Humans
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Ifosfamide / blood
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Infusions, Parenteral
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Mercaptopurine / blood
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Methotrexate / blood
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Paclitaxel / blood
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Platinum Compounds / pharmacokinetics
Substances
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Anthracyclines
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Antibiotics, Antineoplastic
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Antineoplastic Agents
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Platinum Compounds
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Epirubicin
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Doxorubicin
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Mercaptopurine
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Asparaginase
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Paclitaxel
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Fluorouracil
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Ifosfamide
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Methotrexate