Abstract
Sprague-Dawley rats were fed alpha-tocopherol, tocotrienol, or quercetin to examine their dietary effects on serum lipid contents and immunoglobulin productivity. In tocotrienol or quercetin groups, serum triglyceride was lower than in the none group. Moreover, in the alpha-tocopherol group, serum IgA level and IgA productivity of MLN lymphocytes were high, while in the tocotrienol group, IgM productivity of spleen lymphocytes and IgA, IgG, and IgM productivity of MLN lymphocytes were high. Thus, we suggested each antioxidant had different effects in rats.
MeSH terms
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Animals
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Antioxidants / pharmacology*
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Cholesterol / blood
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Diet*
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Immunoglobulin A / biosynthesis
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Immunoglobulin G / biosynthesis
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Immunoglobulin M / biosynthesis
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Immunoglobulins / biosynthesis*
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Lipids / blood*
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Lymphocytes / drug effects*
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Lymphocytes / metabolism
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Male
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Quercetin / pharmacology
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Rats
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Rats, Sprague-Dawley
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Spleen / cytology
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Spleen / drug effects
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Spleen / metabolism
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Triglycerides / blood
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Vitamin E / analogs & derivatives
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Vitamin E / pharmacology
Substances
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Antioxidants
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Immunoglobulin A
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Immunoglobulin G
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Immunoglobulin M
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Immunoglobulins
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Lipids
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Triglycerides
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Vitamin E
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Cholesterol
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Quercetin