Suprasellar cystic germinoma

Childs Nerv Syst. 1999 Mar;15(2-3):134-6. doi: 10.1007/s003810050351.

Abstract

We report on a germinoma in the suprasellar region, which had multiple large cystic components. A 13-year-old girl with disturbed visual acuity and growth retardation was admitted to our hospital for treatment of an intracranial tumor. The lesion was difficult to diagnose as a germinoma preoperatively, because of its radiographic characteristics. Histopathological examination revealed that the tumor was a germinoma. Surgery, chemotherapy with carboplatin and etoposide, and radiotherapy (30 Gy) were successful in inducing complete remission of the tumor. The patient's endocrine status remained normal, except for a low GH concentration and diabetes insipidus.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Brain / diagnostic imaging
  • Brain / pathology*
  • Brain / surgery*
  • Brain Neoplasms / complications
  • Brain Neoplasms / pathology*
  • Brain Neoplasms / therapy
  • Craniopharyngioma / diagnosis
  • Diabetes Insipidus / etiology
  • Diagnosis, Differential
  • Drug Therapy
  • Female
  • Germinoma / complications
  • Germinoma / diagnosis*
  • Germinoma / therapy
  • Human Growth Hormone / blood
  • Humans
  • Magnetic Resonance Imaging
  • Postoperative Complications
  • Radiography
  • Radiotherapy

Substances

  • Human Growth Hormone