[Thrombosis of aortic valve prostheses: its incidence, morphological aspects and surgical treatment]

G Ital Cardiol. 1999 Mar;29(3):277-83.
[Article in Italian]

Abstract

Background: The authors report their experience on the diagnosis, pathological findings and surgical treatment of prosthetic aortic valve thrombosis.

Methods: Between January 1976 and June 1998, 1289 mechanical prostheses were implanted in aortic position at our institution: a prosthetic obstruction was found in 12 cases. Thrombolysis was performed in two cases and as a result, pathological findings were not available and the patients were excluded from the study. Ten patients underwent surgical treatment.

Results: Thrombectomy was performed in one case and prosthetic replacement was done in 9 patients. One patient died postoperatively of low-output syndrome, the others were discharged and no recurrence of thrombosis has been observed at follow-up. Primary thrombosis was found in 6 cases, and pannus formation was observed in 4 patients. All patients with primary thrombosis had a history of poor anticoagulation. Patients with pannus formation had a tilting disc prosthesis.

Conclusions: Use of bileaflet prostheses and adequate anticoagulation can further lessen the incidence of this dreadful complication.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Anticoagulants / therapeutic use
  • Aortic Valve / pathology
  • Bioprosthesis* / statistics & numerical data
  • Female
  • Heart Diseases / epidemiology*
  • Heart Diseases / pathology
  • Heart Diseases / surgery
  • Heart Valve Prosthesis* / statistics & numerical data
  • Humans
  • Incidence
  • Italy / epidemiology
  • Male
  • Middle Aged
  • Postoperative Care
  • Reoperation
  • Retrospective Studies
  • Thrombosis / epidemiology*
  • Thrombosis / pathology
  • Thrombosis / surgery

Substances

  • Anticoagulants