[Increase in the lipid peroxide content in the blood and aortas of rabbits with experimental atherosclerosis]

Vopr Med Khim. 1976 Jul-Aug;22(4):513-7.
[Article in Russian]

Abstract

Content of lipid peroxides was estimated in blood and aorta of intact rabbits by means of highly sensitive polarographic method, using a mercuric electrode. Content of lipoperoxides in blood and aorta was increased 4.4- and 3.6-fold, respectively, in animals with pronounced experimental atherosclerosis. The oxidation of lipoperoxides caused a distinct increase in content of intermolecular bindings in amino-containing phospholipids in aorta of rabbits with pronounced atheromatosis.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Animals
  • Aorta / analysis
  • Aorta / metabolism*
  • Arteriosclerosis / metabolism*
  • Autoanalysis
  • Cholesterol / analysis
  • Diet, Atherogenic
  • Fatty Acids, Unsaturated / analysis
  • Lipid Metabolism*
  • Lipids / analysis
  • Male
  • Peroxides / analysis
  • Peroxides / metabolism*
  • Phospholipids / analysis
  • Polarography / methods
  • Rabbits
  • Spectrometry, Fluorescence
  • Triglycerides / analysis

Substances

  • Fatty Acids, Unsaturated
  • Lipids
  • Peroxides
  • Phospholipids
  • Triglycerides
  • Cholesterol