Abstract
Objective:
To explore the effect of Buyang Huanwu Decoction (BYHWD) on the platelet function and fibrinolytic activity of unstable angina pectoris patients.
Methods:
Using randomized single blind method divided 60 unstable angina pectoris patients into conventional treatment (control) group and conventional plus BYHWD (TCM) group.
Results:
BYHWD could lower the levels of platelet aggregation, thromboxane B2 and the inhibitor of fibrinolysinogen activator (P < 0.05), but the activity of histo-type of fibrinolysinogen activator was enhanced.
Conclusion:
BYHWD was effective in treating unstable angina pectoris.
Publication types
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Clinical Trial
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English Abstract
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Randomized Controlled Trial
MeSH terms
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Adult
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Aged
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Angina, Unstable / blood*
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Angina, Unstable / drug therapy
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Antifibrinolytic Agents / therapeutic use*
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Drugs, Chinese Herbal / therapeutic use*
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Female
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Humans
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Male
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Middle Aged
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Plasminogen Inactivators / blood
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Platelet Aggregation / drug effects*
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Platelet Aggregation Inhibitors / therapeutic use*
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Single-Blind Method
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Thromboxane B2 / blood
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Tissue Plasminogen Activator / blood
Substances
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Antifibrinolytic Agents
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Drugs, Chinese Herbal
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Plasminogen Inactivators
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Platelet Aggregation Inhibitors
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Thromboxane B2
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Tissue Plasminogen Activator