Isolation and characterization of a novel antifreeze protein from carrot (Daucus carota)

Biochem J. 1999 Jun 1;340 ( Pt 2)(Pt 2):385-91.

Abstract

A modified assay for inhibition of ice recrystallization which allows unequivocal identification of activity in plant extracts is described. Using this assay a novel, cold-induced, 36 kDa antifreeze protein has been isolated from the tap root of cold-acclimated carrot (Daucus carota) plants. This protein inhibits the recrystallization of ice and exhibits thermal-hysteresis activity. The polypeptide behaves as monomer in solution and is N-glycosylated. The corresponding gene is unique in the carrot genome and induced by cold. The antifreeze protein appears to be localized within the apoplast.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antifreeze Proteins
  • Base Sequence
  • Blotting, Western
  • Chromatography, Gel
  • Chromatography, Ion Exchange
  • Cloning, Molecular
  • Cold Temperature
  • DNA Primers
  • Daucus carota / chemistry*
  • Electrophoresis, Agar Gel
  • Electrophoresis, Polyacrylamide Gel
  • Glycoproteins / chemistry
  • Glycoproteins / genetics
  • Glycoproteins / isolation & purification*
  • Glycosylation
  • Organelles / chemistry
  • Recombinant Proteins / chemistry
  • Recombinant Proteins / genetics
  • Recombinant Proteins / isolation & purification

Substances

  • Antifreeze Proteins
  • DNA Primers
  • Glycoproteins
  • Recombinant Proteins