[The MRT of focal liver lesions: the value of gadolinium-enhanced dynamic studies of the whole organ with a fast 3D-turbo-gradient echo sequence]

Rofo. 1999 Apr;170(4):351-7. doi: 10.1055/s-2007-1011053.
[Article in German]

Abstract

Purpose: To determine the value of a dynamic Gd-enhanced ultrafast T1-weighted 3D-turbo-gradient-echo sequence (3D-TFE) in the detection and characterization of focal liver lesions.

Materials and methods: 51 patients with 124 focal liver lesions (35 hemangiomas, 30 HCC, 24 metastases, 22 cysts, 5 FNH/adenoma, 8 other lesions) were examined using a 1.5 T system. The dynamic 3D-TFE sequence, achieving 40 slices with a thickness of 4.5 mm in a 17-s breath-hold, was compared with a fat-suppressed T2-weighted fast-spin-echo sequence (TSE SPIR), unenhanced and Gd-enhanced T1-weighted spin-echo sequences (SE), and a T1-weighted gradient-echo sequence (FFE).

Results: On 3D-TFE images more lesions (107/124) were identified than on T1-weighted SE (101/124) and T1-weighted FFE images (106/124), but less compared to T2-weighted TSE SPIR images (115/124). The 3D-TFE-sequence provided additional information in 65/107 (61%) detected lesions by delineating the dynamic enhancement pattern, most valuable in patients with HCCs in 90%.

Conclusions: On dynamic 3D-TFE images more lesions could be depicted than on conventional T1-weighted SE and T1-weighted FFE images. Visualization of the dynamic enhancement pattern provided additional information for tumor characterization in 61% of the detected lesions on the 3D-TFE images.

Publication types

  • Comparative Study

MeSH terms

  • Artifacts
  • Contrast Media*
  • Gadolinium DTPA*
  • Humans
  • Liver / diagnostic imaging
  • Liver / pathology*
  • Liver Neoplasms / diagnosis*
  • Liver Neoplasms / secondary
  • Magnetic Resonance Imaging / instrumentation
  • Magnetic Resonance Imaging / methods*
  • Magnetic Resonance Imaging / statistics & numerical data
  • Sensitivity and Specificity
  • Statistics, Nonparametric
  • Time Factors
  • Tomography, X-Ray Computed
  • Ultrasonography

Substances

  • Contrast Media
  • Gadolinium DTPA