Abstract
Dermatomyositis, polymyositis, and inclusion body myositis are rare illnesses which appear to be distinct in clinical and pathologic features, pathogenesis, natural history, and response to therapy. We report two patients who first developed dermatomyositis, and then, after a disease-free interval of many years, developed inclusion body myositis. This may have useful therapeutic implications for patients with dermatomyositis whose illness bocomes refractory to treatment.
MeSH terms
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Adult
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Azathioprine / therapeutic use
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Creatine Kinase / blood
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Dermatomyositis / complications*
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Dermatomyositis / drug therapy
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Dermatomyositis / enzymology
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Dermatomyositis / pathology
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Humans
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Male
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Middle Aged
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Muscle, Skeletal / pathology
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Myositis, Inclusion Body / complications*
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Myositis, Inclusion Body / drug therapy
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Myositis, Inclusion Body / enzymology
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Myositis, Inclusion Body / pathology
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Prednisolone / therapeutic use
Substances
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Prednisolone
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Creatine Kinase
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Azathioprine