Use of Tc-99m DTPA galactosyl human serum albumin to predict postoperative residual liver function

Clin Nucl Med. 1999 Jun;24(6):428-34. doi: 10.1097/00003072-199906000-00011.

Abstract

Purpose: Residual liver uptake at 15 minutes (RLU15), a new index for predicting residual liver function after excision of hepatocellular carcinoma, was evaluated using dynamic liver images and SPECT by Tc-99m DTPA galactosyl human serum albumin.

Materials and methods: In 13 cases of hepatectomy, RLU15 was compared with postoperative serum prothrombin levels, serum bilirubin levels, and ascites.

Results: RLU15 showed good correlation with both the prothrombin activity and the serum bilirubin, with correlation coefficients of r = 0.829 and r = -0.757.

Conclusion: This new index appears useful for predicting residual liver function after hepatectomy.

Publication types

  • Case Reports

MeSH terms

  • Ascites
  • Bilirubin / blood
  • Carcinoma, Hepatocellular / diagnostic imaging
  • Carcinoma, Hepatocellular / surgery*
  • Evaluation Studies as Topic
  • Hepatectomy
  • Humans
  • Liver / diagnostic imaging
  • Liver / metabolism*
  • Liver Function Tests / methods*
  • Liver Neoplasms / diagnostic imaging
  • Liver Neoplasms / surgery*
  • Male
  • Middle Aged
  • Prothrombin / analysis
  • Radiopharmaceuticals*
  • Technetium Tc 99m Aggregated Albumin*
  • Technetium Tc 99m Pentetate*
  • Tomography, Emission-Computed, Single-Photon*

Substances

  • Radiopharmaceuticals
  • Technetium Tc 99m Aggregated Albumin
  • Prothrombin
  • Bilirubin
  • Technetium Tc 99m Pentetate